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Ocular characteristics in Marfan syndrome
Marfan syndrome (MFS) is a genetic disorder with clinical manifestations associated with cardiovascular, ocular and skeletal organ systems. Typical signs are descending aortic root aneurysms, ectopia lentis, tall stature and scoliosis. This observational study looked at the ocular characteristics, visual...
Enzymatic clearance of anterior chamber infiltrate in uveitis
Aqueous humour (AH) which fills the anterior chamber (AC) of the eye provides nutrients to the cornea and the lens. Clearance of cellular and particular matter from AH is necessary for good visual acuity. In part this is achieved by...
Glasses or not?
In this excellent review article, the authors discuss how some hyperopes avoid strabismus but also ask why the youngest infants escape strabismus and older patients go on to decompensate. The review considers a number of related aspects and their inter-relations...
Differential diagnosis of inflammatory optic neuritis
The authors present the differential diagnosis of inflammatory optic neuritis (ON) to include multiple sclerosis, infectious optic neuritis, systemic disease and neuromyelitis optica (NMO). The features of ON for the varying aetiologies are detailed including incidence and overlap. In acute...
Microperimetry of subretinal drusenoid deposits
Subretinal drusenoid deposits (SDD), originally termed ‘reticular pseudo-drusen’, have recently been identified by histology and optical coherence tomography (OCT) as aggregations located in the subretinal rather than the sub retinal pigment epithelium (RPE) space. These deposits affect the amount of...
Photoscreening comparison
The A09/S09 photoscreener contains a fixation target of flashing lights (as for the S04) plus a smiley face which is new. Concerns were raised that the smiley face may stimulate less accommodation than the S04 attention lights and therefore potentially...
Macular oedema after cataract surgery in diabetic patients
The authors describe a multi-centre prospective observational study of 293 participants that underwent cataract surgery who all had diabetic retinopathy without definite central-involved macular oedema. Forty-five clinical sites took part throughout the United States. Patients were eligible if there was...
Impact of medical vs. surgical treatment on quality of life in glaucoma patients
The author recruited 225 patients across two sites and divided them into three groups. Group 1 medical treatment only, Group 2 surgical treatment only, Group 3 mixed medical and surgical (patients still on drops after surgery). They then used a...
Time domain vs. spectral domain in the measurement of the optic nerve head
The authors describe a prospective study of 40 participants (20 healthy and 20 with glaucoma) enrolled to compare the measurements of the optic nerve head (ONH) parameters given by time domain (TD) and spectral domain (SD) optical coherence tomography (OCT)....
Molecular genetics of achromatopsia
Achromatopsia is a rare autosomal recessive disorder of the cone photoreceptors. Typical characteristics of affected patients include the inability to distinguish colours, impaired visual acuity, photophobia and nystagmus. The condition is said to be more frequent in the Pingelapese population...
Effect of refractive corneal surgery on IOP and glaucoma progression
Accuracy of intraocular pressure (IOP) measurement depends on the biomechanical properties of the cornea, including its thickness central corneal thickness (CCT) and keratometry (K). Fifty-six eyes of 56 patients with primary open angle glaucoma (POAG) who had a history of...
