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How common is optic disc drusen in young patients with NAION?
A retrospective notes review at two tertiary care centres was completed between 2009 and 2019. The inclusion criteria for the study was a diagnosis of nonarteritic anterior ischaemic optic neuropathy (NAION) in at least one eye, aged between 18 and...
AI glaucoma screening cost-effective in the Netherlands?
Population-wide screening for glaucoma has traditionally been deemed not cost-effective due to high costs and low disease prevalence. This Dutch study re-evaluates this position by introducing artificial intelligence (AI) to the screening model. The authors developed a health-economic model comparing...
A prospective trial of adjuvant therapy for high-risk melanoma
Patients diagnosed with iris, ciliary body or choroidal melanoma of high-risk tumour cytogenetics (monosomy 3>/= 20% of cells), were treated with adjuvant low-dose dacarbacine (DTIC) and interferon –alpha-2b (IFNA-2b), following primary treatment (enucleation, brachytherapy or resection). DTIC was given intravenously...
PD-1 and retinal ganglion cell death
Death of retinal ganglion cells (RGC) in conditions like glaucoma leads to permanent visual loss. RGC death can be due to the initial stress such as raised intraocular pressure or secondary to mechanism such as oxidative stress. Programmed cell death-1...
Human leucocyte antigen association of patients with Stevens-Johnson syndrome in Han Chinese
This is a retrospective study of the human leucocyte antigen (HLA) polymorphism pattern of cold medicine-induced patients with Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) (n=33) and 98 control patients recruited between 2016-2017 in Taiwan. Severe ocular complications (SOC) was...Understanding spaceflight-associated neuro-ocular syndrome (SANS): what do we know?
Introduction Formerly known as visual impairment and intracranial pressure syndrome (VIIP), space-related neuro-ocular syndrome (SANS) is defined by a collection of ophthalmic and neurological findings in astronauts after long-term spaceflight [1]. Changes in the eyeball, such as hyperopic shift, during...
Outline of clinical care for healthy newborns with uncomplicated conjunctivitis in the US
The purpose of this study was to explore the current state of clinical care for healthy newborns with uncomplicated ophthalmia neonatorum (ON) using a large electronic health record dataset. Despite the existence of national guidelines for antepartum screening for N....How to get the most out of your medical school ophthalmology placement
Ophthalmology has become a very popular speciality, generating a vast interest amongst medical students with competition for training posts increasing yearly. Yet it is often difficult to get adequate exposure to the speciality prior to applications, with very limited time...AOP fee reduction for members amidst coronavirus crisis
The Association of Optometrists (AOP) has announced a 20% reduction in membership fees for UK practising members, which is the equivalent of two monthly direct debit payments.
Prevalence and risk factors for ROP in Saudi Arabia
This study aimed to establish the prevalence of retinopathy of prematurity (ROP) among high-risk neonates in a tertiary centre, identify the most commonly associated risk factors and highlight the benefits of early treatment of type 2 ROP and ROP milder...
Trabeculectomy ab interno (trabectome)
This retrospective study examines the outcome of trabectome surgery in nine phakic patients with Posner-Schlossman syndrome with uncontrolled IOP >30mmgHg. Cytomegalovirus (CMV) DNA was verified by polymerase chain reaction (PCR) in aqueous humour samples. Patients were treated with oral valganciclover...
