You searched for "myasthenia"
Ocular findings in children with myasthenia
This is a retrospective audit of paediatric myasthenic patients presenting to Great Ormond Street (GOSH) between January 2016 and January 2020. During this period there were 49 children, including 27 with juvenile myasthenia (JMG) and the rest as congenital myasthenia...Myasthenia Gravis Masquerading as a Third Cranial Nerve Palsy
1 February 2014
| Maria Loredana Popescu, Annabel Doyle
A 65-year-old man presented with a week’s history of binocular diplopia (in all directions of gaze) and a right partial ptosis. He was systemically well. His past medical history was unremarkable except for vitiligo. At presentation acuity was 6/6 bilaterally....
Assaying acetylcholine receptor antibodies in the diagnosis of ocular myasthenia
1 December 2022
| Claire Howard
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EYE - Neuro-ophthalmology
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Ocular myasthenia, anti-acetyl choline receptor antibody, generalised myasthenia
Myasthenia gravis (MG) is an autoimmune disease that leads to impaired neuromuscular transmission. Solely ocular manifestations of MG (OMG) occur in 15-50% of cases, most frequently in the form of fluctuating ptosis and diplopia. Most cases of OMG convert later...
Myasthenia gravis presenting with isolated ptosis: a poorly studied subgroup
1 February 2015
| B Karri, RT Sebastian, G Kyle, IK Hart
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EYE - Vitreo-Retinal
Investigation into the cause of one isolated symptom or sign can be challenging if that particular sign may be caused by a variety of pathological processes, affecting different tissues, and presenting to different specialties. Unilateral ptosis is a case in...
Incidence of ocular myasthenia gravis and risk factors for conversion to generalised disease
This population based retrospective cohort study evaluates the incidence of ocular myasthenia gravis (OMG) as well as risk factors for transformation to generalised myasthenia gravis (GMG). Sixty-five patients (40 male and 25 female) with newly diagnosed with myasthenia gravis (MG)...Acetylcholine receptor antibodies in the diagnosis of ocular myasthenia gravis at the Manchester Royal Eye Hospital
3 August 2023
| Nouf Alnafisee, Joanna M Jefferis
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EYE - Neuro-ophthalmology
Myasthenia gravis (MG) is the commonest autoimmune condition to affect the neuromuscular junction. In the UK, its prevalence is 15 per 10,000 [1,2] and recent studies have shown that rates are steadily increasing [3,4]. Aims of this audit The aim...
Serology testing in periocular inflammatory disease
This is a review article of serological tests in thyroid eye disease, IgG4-related disease and myasthenia gravis. The authors provide an overview of the current serology with a brief description of how they relate to the pathogenesis of each condition....
Steroid safety in MG treatment
This study was conducted to evaluate the efficacy and safety of low to moderate dose oral steroids in patients diagnosed with ocular myasthenia gravis (MG). This was a retrospective case series. The study reviewed 23 patients; 15 males and eight...Managing a patient with ptosis
A 50-year-old male patient is referred from the Accident & Emergency department with a history of ptosis. How will you manage this patient? Mr Bertie Fernando Clinical management Clinical management starts with a sound clinical history. Current history The history...
Globe subluxation subsequent to long-term steroids
Globe subluxation, when the globe equator projects anterior to the orbital rim, is a serious orbital condition commonly associated with thyroid eye disease, floppy eye syndrome or a shallow orbit. The authors present a first case of a spontaneous globe...Third nerve palsy
1 August 2017
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EYE - Neuro-ophthalmology, EYE - General
Case scenarios A 71-year-old female presented to a nearby eye emergency unit with two days history of partial ptosis in her left eye with diplopia. She saw her GP earlier that day and he asked her to go to the...
North West Neuro-Opthalmology Day
6 July 2022
The inaugural North West Neuro-Ophthalmology course aims to cover a variety of clinical neuro-ophthalmic complaints via succinct, interactive lectures. The lectures are delivered by a range of consultants specialising in neurology, neuro-ophthalmology, neuro-radiology, orbital disease and uveitis. The course will...
