The authors aimed to characterise a large international cohort of children with nystagmus. Data were taken from a prospective database which was started in 2010. Up to 2020, this contained 1774 patients with nystagmus from 38 US states and 30 countries. Six hundred were aged <18 years. All had >1 year follow-up. Mean age was 15 ±14 years; 58% female, 42% male, 45% white. Infantile nystagmus syndrome was present in 449 (75%). One-hundred-and-four had neuro nystagmus, 37 with fusion maldevelopment nystagmus, and ten with spasmus nutans. Strabismus was present in 64% and 56% had an abnormal head posture. Significant refractive error was present in 94%. Most with infantile nystagmus syndrome had an eccentric null zone, strabismus and ametropia. Acquired types were mostly pendular or vestibular nystagmus. Treatment for 95% included optical, medical and / or surgical options.
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Types of nystagmus and associations in a large international database for nystagmus
Reviewed by Fiona Rowe
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Fiona Rowe (Prof)
Institute of Population Health, University of Liverpool, UK.
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