The compendium to clinical evidence in DMO treatment
Reviewed by Zhihang Cheng

This review article summarises the current evidence base in the treatment options for diabetic macular oedema (DMO). The authors have included many real-world data studies that provided valuable insights into the optimal management of DMO. The authors argue that these studies, when combined with randomised control trial (RCT) data, provide the most effective evidence-based DMO guidelines. In addition, the authors suggest that real world data will identify low frequency safety signals notably for novel approved drugs. Lastly, the authors draw attention to emerging technologies like AI, big-data or software linkage and how they will increase the utilisation of real-world data.

From randomised controlled trials to real-world data: Clinical evidence to guide management of diabetic macular oedema.
Gabrielle PH, Mehta H, Barthelmes D, et al.
PROGRESS IN RETINAL AND EYE RESEARCH
2023;97:101219.