The authors present a retrospective review of clinical and imaging data from a stroke database over a 10-year period. Of those identified as having a thalamic infarction (n=342), 40 were found to have neuro-ophthalmic sequelae (11.7%). The neuro-ophthalmic sequelae reported in this group of patients included vertical gaze palsy, skew deviation, ptosis with and without associated miosis and visual field defects. Neuro-ophthalmic sequelae was reported to be most associated with infarctions related to the paramedian artery. Whilst a large number recovered within the first three months post-stroke, a fifth were reported to have residual neuro-ophthalmic sequelae beyond 12 months post-stroke. This study demonstrates that a wide range of neuro-ophthalmic sequelae can occur as a result of thalamic infarction, which can persist long-term. It also adds to the body of evidence supporting the screening of patients presenting with stroke for neuro-ophthalmic sequelae.