A prospective study collecting quality of life data from children with a wide range of eye conditions, as well as visually normal controls using the Pediatric Eye Questionnaire (PedEyeQ) between the ages 0 and 17 years. One thousand and thirty-seven children with at least one of 13 different eye conditions and 254 children with normal uncorrected vision. The scores on the PedEyeQ indicated a lower quality of life across all age ranges when compared to the visually normal controls. The use of the Parent PedEyeQ revealed that this extended to parents of children with eye conditions having significantly poorer quality of life than parents of visually normal children. This study does not show how specific conditions impact on quality of life in detail, but it does highlight areas of interest for future research.