This retrospective review compared combined phacoemulsification and endoscopic cyclophotocoagulation (phaco-ECP) to phaco alone in patients with mild to moderate glaucoma. Outcome measures included cumulative full and qualified success survival, postintervention IOP and ocular anti-hypertensive medication reduction. Full success was defined as a minimum of 20% reduction of IOP with a decrease in at least one ocular anti-hypertensive medication, qualified success was defined as an IOP no higher than preoperative with a decrease in at least one ocular anti-hypertensive medication. There were 261 eyes in the phaco-ECP group and 52 eyes in the phaco alone group. All patients were diagnosed with mild to moderate glaucoma controlled medically preoperatively with one to three ocular anti-hypertensive medications. Results showed that both phaco-ECP and phaco alone effectively lowered the IOP in the long-term when compared to baseline. At 36 months, the mean number of medication reliance in the phaco-ECP group was 0.2 compared to 1.3 in the phaco alone group; 61.4% reached full success in the phaco-ECP group compared to 23.3% in the phaco alone group. In the phaco-ECP group 72.6% reach qualified success compared to 23.3% in the phaco alone group. All these results were statistically significant. Complications that occurred in the phaco-ECP group included cystoid macula oedema (four cases), retinal detachment (two cases), the need for secondary glaucoma procedures (seven cases) and the need for a penetrating keratoplasty (one case). In conclusion, combined phaco-ECP is more effective in treating mild to moderate glaucoma when compared to phaco alone.