This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies.  Read our Cookies Policy.
Close
Eye News
  • Features
    • Close
    • Features
    • Allied Professions
    • Humanitarian
    • Interviews
    • AI & Oculomics
    • Ophthalmology
    • Optometry
    • Podcast videos
    • Supplements
  • Education
    • Close
    • Education
    • Learning Curve
    • Quiz
    • Top Tips
    • Trainees
    • Medico-Legal
    • The Truth Behind The Headlines
    • Case Reports
    • Pete's Bogus Journey
  • Reviews
    • Close
    • Reviews
    • Book Reviews
    • Journal Reviews
    • What's trending?
    • Tech Reviews
    • My Top Five
    • The Culture Section
  • Events
  • News
  • Product Guide
  • Industry News
  • Contact us
    • Close
    • Contact us
    • Write for Eye News
  • Home
  • Reviews
  • Journal Reviews
  • Orbital manifestations of granulomatosis with polyangitis

Orbital manifestations of granulomatosis with polyangitis
Reviewed by Rina Bhatt

4 February 2021 | Rina Bhatt | EYE - Oculoplastic, EYE - Orbit
Share This

This a retrospective, observational study where authors looked at the ophthalmological examination, biopsy, antibodies and CT scan results of all patients diagnosed with granulomatosis with polyangitis (GPA) from January 2007-January 2019. Out of 101 patients with diagnosis of GPA, 15 (14.8%) with orbital manifestations were included in the study. Eleven (73.3%) were female and mean age at diagnosis was 46.20 years. Proptosis was seen in 11 (73.3%) cases and another four had dacryocystitis, a palpebral laceration, a nasal septum destruction with extraconal mass and diplopia. The lacrimal gland was involved on CT scan in five (33.3%) cases. Other radiological findings were a diffuse extraconal or intraconal mass, lacrimal sac involvement and extraocular muscle involvement; 14 (93.3%) were biopsy confirmed. Histology showed necrosis surrounded by granulomatous inflammation and sectorial fibrinoid necrosis in walls of small calibre blood vessels. Once diagnosed, patients were treated with Prednisone 1mg/kg and referred to rheumatology for joint management.

Orbital manifestations of granulomatosis with polyangitis: 12-year experience in Mexico City.
Davila-Camargo A, Tovilla-Canales JL, Rodrigues-Cabrera L, et al.
ORBIT
2020;39:357-64.
Share This
CONTRIBUTOR
Rina Bhatt

Wolverhampton Eye Infirmary, UK.

View Full Profile
Specialty
  • EYE - Cataract
  • EYE - Cornea
  • EYE - General
  • EYE - Glaucoma
  • EYE - Neuro-ophthalmology
  • EYE - Oculoplastic
  • EYE - Oncology
  • EYE - Orbit
  • EYE - Paediatrics
  • EYE - Pathology
  • EYE - Refractive
  • EYE - Strabismus
  • EYE - Vitreo-Retinal
Archive
  • 2025
  • 2024
  • 2023
  • 2022
  • 2021
  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013

Top Of Page

9 Gayfield Square, 
Edinburgh EH1 3NT, UK.

Call: +44 (0)131 557 4184
www.pinpoint-scotland.com

WEBSITE DETAILS
  • Cookie Policy
  • Data Protection Notice
  • Privacy Policy
  • Terms and Conditions
ABOUT US
  • Who we are
  • Register
  • Contact us
  • Contributors
  • Company Awards
DIGITAL ISSUES/GUIDELINES
  • Digital issues - Library
  • Supplements - Library
  • Guidelines
Accreditations
IPSO_FLAG_TEAL 2025.png cpdcertified.png

Pinpoint Scotland Ltd (Registered in Scotland No. SC068684) | © 2025 - Website by Gecko Agency