Optic disc pit maculopathy: an optical coherence tomography study
Reviewed by Sofia Rokerya

This was a single-centre, retrospective observational case series that aimed to analyse the change of optical coherence tomography (OCT) characteristics in the natural course of optic disc pit maculopathy (ODP-M) and their effects on visual acuity. Twenty-two eyes of 22 patients that met the inclusion criterion were evaluated. The mean age of the patients was 36.2 years (median 32) and 11 (50%) of them were female. In 13 patients (59%), the right eye was involved. The mean follow-up period was 38 months. Baseline demographic characteristics, central macular thickness (CMT), intrapapillary proliferation (IPP), subretinal fluid (SRF), subretinal precipitations, outer retinal fluid (ORF) and outer retinal layer hole were evaluated. The changes in the OCT characteristics were analysed, with respect to the best corrected visual acuity (BCVA) from baseline to the last visit. Patients were divided into three groups as improved BCVA (1), stable BCVA (2) and decreased BCVA (3), if a change of BCVA of at least 0.1 logMAR was recorded from the baseline to the last visit. Regarding the location of the optic pit, records showed: temporal (12), inferotemporal (6) superotemporal (2) and central (2). The ODP-M was found in 54% of the patients with ODP. The mean BCVA was 0.31 logMAR at baseline and 0.28 logMAR at the final visit (p = 0.521). The baseline BCVA was significantly related to CMT (β coefficient 0.001, p = 0.002). Mean BCVA increased in seven patients (group 1), remained stable in nine (group 2) and decreased in six patients (group 3). No significant difference was found between the groups regarding the baseline BCVA, CMT and extent of retinal fluid. In patients with subretinal deposits, BCVA remained stable in three patients and worsened in one. ORF was recorded in all patients. In patients with SRF, the mean change of BCVA during follow-up differed significantly, depending on the presence (0.07 logMAR) or absence (-0.125 logMAR) of SRF (p = 0.019). IPP was detected in 60% of the patients who had better baseline BCVA and a lower rate of SRF. The study concluded that SRF was found to be a negative prognostic factor for vision. BCVA of patients without SRF may remain stable or have the potential to improve over three years. Limitations of the study include its retrospective design and small cohort. Also, the study lacks data on fluid characteristics and the changes in IPP.

Natural course of optic disc pit maculopathy: an optical coherence tomography study.
Uzel AGT, Gelisken F, Bartz-Schmidt KU, Neubauer J.
OPHTHALMOLOGICA
2022;245:563-9.