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This study aimed to evaluate the macular parameters including foveal avascular zone (FAV) size and vessel density in amblyopia vs fellow eyes. The study included 23 unilateral amblyopia children (9.86 ±3.12 years; 52.2% female) and non-amblyopia control eyes (8.67 ±2.06 years; 60.9% female). Visual acuity was 0.17 ±0.13 logMAR for amblyopia eyes, 0.01 ±0.03 for fellow eyes and 0.02 ±0.04 for control eyes. Mean spherical equivalent was +2.21 ±2.07D, +1.80 ±1.97 and +0.61 ±1.48 respectively. Whole vessel density was significantly lower in control eyes vs amblyopia and fellow eyes: 46.89 ±4.03, 49.19 ±2.99 and 49.87 ±4.14 respectively. Deep capillary plexus was significantly greater in control eyes than fellow and amblyopic eyes: 46.84 ±4.16, 47.82 ±4.0 respectively. There was a larger foveal avascular zone in amblyopic vs fellow eyes: 0.26 ±0.06mm2, 0.21 ±0.07 and 0.22 ±0.118 respectively. There was no significant difference for foveal, parafoveal and perifoveal superficial and deep vascular densities. Deep whole density of amblyopic eyes was lower and indicates decreased blood supply of amblyopic eyes in this region.

Optical coherence tomography angiography in patients with amblyopia.
Nourinia R, Rajavi Z, Sabbaghi H, et al.
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Fiona Rowe (Prof)

Institute of Population Health, University of Liverpool, UK.

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