Femtosecond laser cataract surgery (FLACS) is being increasingly used in the preparation for cataract surgery. Benefits of circular capsulorrhexis and reduced phacoemulsification energy have been shown in the literature. This study was designed to assess the anterior chamber characteristics and their correlation to laser flare photometry after FLACS in comparison to conventional phacoemulsification. A prospective study was designed in accordance with the Declaration of Helsinki. One hundred and ten patients were enrolled and separated into two groups – FLACS group (n=70) and Manual Phacoemulsification group (n=40). LenSx Alcon femtosecond machine was used to carry out the FLACS procedure with standard capsulorrhexis of 5mm and laser pulse energy of 4.8uJ for capsulorrhexis and 8.9uJ for nucleus fragmentation. Results showed a significant difference in the AC depth at one day postop. The central and thinnest corneal thickness and endothelial cell count did not show significant difference between the two groups. The anterior chamber flare was also found to be statistically insignificant. Therefore this study supports no difference or increase in the anterior chamber flare or inflammation after femtosecond cataract surgery with the use of LenSx Alcon femtosecond system.