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  • Congenital aniridia clinical features

Congenital aniridia clinical features
Reviewed by Fiona Rowe

1 October 2014 | Fiona Rowe (Prof) | EYE - Paediatrics, EYE - Strabismus

In this study the authors investigated the various ocular and systemic features associated with congenital aniridia in Indian eyes (262 eyes of 131 patients). The median age at time of first hospital visit was eight years (one day to 73 years). There were 51% male and 49% female. Ninety-seven percent had bilateral aniridia, one unilateral and one normal. The median visual acuity at presentation was 1.0 logMAR (0.10-2.10). Fifty-six percent had horizontal jerk nystagmus. Corneal involvement was seen in 60%. Phakic lens status was in 94%. Others were pseudophakic or aphakic. Cataract was present in 38.5%, subluxation in 22%, foveal hypoplasia in 88%, vitreous opacities in 16%. A pale disc was present in 13 eyes, hypoplastic in seven eyes. Three had retinal detachment. Glaucoma was present in 36%. Males had higher proportion of associated subluxation. There was no gender preponderance for glaucoma and cataract. The authors conclude that aniridia is commonly associated with other ocular features but systemic associations were notably absent.

Clinical manifestations of congenital aniridia.
Singh B, Mohamed A, Chaurasia S, et al.
JOURNAL OF PEDIATRIC OPHTHALMOLOGY AND STRABISMUS
2014;51:59-62.
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Fiona Rowe (Prof)
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Fiona Rowe (Prof)

Institute of Population Health, University of Liverpool, UK.

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