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The authors investigated whether a 15-minute monocular occlusion test is as effective as the traditional 45-minute monocular occlusion test in assessing patients with divergence excess intermittent exotropia. The prospective, randomised observational study included 22 children aged 5–14 years. Children with pre-existing factors which could affect the ocular deviation measurement, or a significant neurological condition, had previous ocular surgery or botulinum toxin injections, were excluded. Researchers compared the effects on ocular deviation (alternate prism cover test), AC/A ratio, and the classification of exotropia subtypes. No statistically or clinically significant differences between the 2 testing durations was found. The prospective design and direct comparison of the 2 protocols strengthen the validity of the findings. The results suggest that a shorter 15-minute monocular occlusion test could reliably replace the 45-minute test, improving patient convenience and clinic efficiency. However, the authors report the following limitations: small sample size and measurements were performed by an unmasked examiner. The study addressed a highly applicable question to everyday practice, where reducing clinic time without compromising diagnostic accuracy is valuable. This study provides evidence for a simpler assessment protocol while maintaining diagnostic reliability.

Fifteen-minute monocular occlusion test compared with 45-minute monocular occlusion test in the evaluation of divergence excess intermittent exotropia.
Uzbak S, Walsh L, Smith D, Wan MJ.
JOURNAL OF THE AMERICAN ASSOCIATION FOR PEDIATRIC OPHTHALMOLOGY AND STRABISMUS
2025;29:104252.
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CONTRIBUTOR
Lauren R Hepworth

University of Liverpool; Honorary Stroke Specialist Clinical Orthoptist, Northern Care Alliance NHS Foundation Trust; St Helen’s and Knowsley NHS Foundation Trust, UK.

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