Journal Reviews
Anatomical and functional outcomes following switching from aflibercept to ranibizumab in NARMD
This is a six-month, prospective, single-arm study in the UK and Germany. A total of 100 patients were enrolled (one in the primary failure group, 99 in the suboptimal treatment response group), treated three-monthly intravitreal ranibizumab injections (0.5mg), and then...
Colour Doppler imaging before and after orbital decompression in thyroid eye disease
In this prospective, uncontrolled study euthyroid patients with moderate to severe inactive thyroid eye disease underwent colour Doppler imaging before and after orbital decompression. Patients with dysthyroid optic neuropathy, corneal breakdown, systemic disease (diabetes, cerebrovascular accident, cardiovascular and peripheral vascular...
Progression of retinitis pigmentosa
This retrospective study evaluates the rate of progression of retinitis pigmentosa (RP) using multimodal imaging, including spectral-domain optical coherence tomography (SD-OCT), fundus autofluorescence (FAF) and microperimtery (MP). Traditional tests used to evaluate RP, for example, Goldmann visual fields and ERG...
Features of Behcet’s disease
This is a retrospective single centre study from Paris, France, between the periods of 1986 to 2015. Twenty-nine out of 217 (13.3%) neuro-Behcet’s disease (NBD) patients presented with neuro-ophthalmic manifestations (55% of men and mean age of 28 years). Sixteen...
Corpus callosum in infantile esotropia
Diffusion tensor imaging (DTI) imaging was undertaken with four infantile esotropia (IE) patients and nine controls. All with IE showed an asymmetrical distribution of callosal fibres when comparing two hemispheres. Many fibres terminated near the tips of the occipital cortices....
Knobby eye syndrome
This study used high resolution MRI to demonstrate and evaluate globe shape in axial high myopia and identify and characterise those with prominent equatorial staphylomata that deflect extraocular muscle paths and presumably alter motility patterns in strabismus. The study included...
Macular pigment and dark adaptation in older population with normal maculas
Macular pigment (MP) such as lutein, zeaxanthin and meso-zeaxanthin are highly concentrated in the fovea. They protect the retina from damage of ambient blue light via antioxidant properties. In older eyes with normal healthy retina, macular pigment optical density (MPOD)...
Imaging requests for CNP
The authors sought to answer the question of to what extent do differences in policy exist between ophthalmologists and neurologists regarding imaging by MRI of patients with acquired ocular cranial nerve palsy (CNP). They conducted a literature review leading to...
Radiologic characteristics of cavernous venous malformations
This study is a retrospective review of cases with a preoperative radiologic diagnosis of cavernous venous malformations (CVMs) over 30 years. The aim of this study was to define imaging characteristics of CVMs, which will help differentiate these lesions from...
Stromal cell alignment in damaged cornea
Stromal keratocytes are responsible for wound healing in the cornea following damage. Keratocytes at the site of injury become activated and differentiate to myofibroblasts which secrete extracellular matrix (ECM) to close the wound, a response mediated by transforming growth factor...
Automated Bruckner device accuracy
The authors developed a Bruckner device, examined volunteers and determined the relation between the luminance of the red fundus reflex and eye rotation. Eye rotation was varied continuously both horizontally (-7 to 8 degrees) and vertically (five degree total range)...
SS-OCT assessment of ITC after phacoemulsification
This is a multicentre randomised controlled trial of 22 patients with primary angle closure glaucoma with peripheral anterior synechia and peripheral primary angle closure glaucoma (PACG) with peripheral anterior synechia (PAS) detected by indentation gonioscopy was randomised into two groups....
