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Journal Reviews

Brolucizumab in age-related macular degeneration, HAWK Study

3 October 2023 | Kurt Spiteri Cornish | EYE - Vitreo-Retinal | Neovascular age-related macular degeneration, aflibercept, anti-vascular endothelial growth factor therapy, brolucizumab, commercial formulation

The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...

Ophthalmologica journal cover image.

Progression of macular atrophy on long-term anti-VEGF therapy for AMD

3 October 2022 | Sofia Rokerya | EYE - Vitreo-Retinal | Anti-VEGF therapy, Long term, Macular atrophy, neovascular age-related macular degeneration

This retrospective study evaluated the progression of macular atrophy in 53 eyes of 53 patients receiving AntiVEGF Therapy for age-related macular degeneration (nAMD), for at least six years. None of the patients had any macular atrophy (MA) at presentation. MA...

Seminars in Ophthalmology journal cover image

The effects of anti-VEGF therapy for NvAMD on retinal vasculature

4 August 2021 | Su Young | EYE - Vitreo-Retinal | aflibercept, foveal avascular zone, neovascular age-related macular degeneration, ranibizumab, retinal vessel density

This retrospective consecutive case series examined 54 eyes of 54 treatment-naïve neovascular age-related macular degeneration (N-AMD) patients. Thirty-three eyes received intravitreal aflibercept injections, and 21 eyes received intravitreal ranibizumab injections with unaffected fellow eyes (54 eyes) as controls. All image...

Acta Ophthalmologica journal cover image.

Wet AMD outcomes post cataract surgery

3 June 2021 | Kareem Waleed Alsaffarini | EYE - Cataract, EYE - Refractive | age-related cataract, antivascular endothelial growth factor, cataract surgery, wet age-related macular degeneration

The authors present the findings of a retrospective study looking at the progression of wet age-related macular degeneration (AMD) in patients who underwent cataract surgery. They recruited a series of 111 patients of which 38 were men and 73 were...

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