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Journal Reviews

Squamous metaplasia of conjunctival epithelial cells with soft contact lens wear versus non-lens wearers

1 December 2014 | Sharmina Khan | EYE - Cornea, EYE - Pathology, EYE - Oncology, EYE - General

Conjunctiva is composed of non-squamous epithelial cells interspersed with goblet cells, which is a secretory epithelium. Squamous metaplasia is a transformation to non-secretory epithelium, ‘keratinised’ and enlargement of the conjunctival non-goblet cells and relatively shrunken nuclei are seen on impression...

Accelerated (9mW/cm2) corneal collagen cross-linking for keratoconus

1 December 2014 | Sharmina Khan | EYE - Cornea, EYE - General, EYE - Pathology, EYE - Oncology

This is one of many studies published / to be published on corneal collagen cross-linking that has a treatment time of 10 minutes compared to the previous Dresden protocol of 30 minutes to halt progression of keratoconus. Much has changed...

Inhibiting high-risk corneal allografts

1 October 2014 | Graham Wallace | EYE - Cornea, EYE - General | T regulatory cells, Tim-1, high-risk corneal allograft rejection, mice

The cornea is an immune privileged site and as such corneal transplants are very successful. However, in situations where this privilege is lost the failure rises substantially. To combat rejection inhibition of the immune responses depends on steroids and other...

Effect of preservative free fluoroquinolones on human corneal epithelial cells in vitro

1 October 2014 | Bheemanagouda Patil | EYE - Cornea, EYE - General

Fluoroquinolones, including second generation (ofloxacin and ciprofloxacin), third generation (levofloxacin and tosufloxacin) and fourth generation (gatifloxacin and moxifloxacin), are a group of bactericidal agents used to treat multiple ocular infections. The third and fourth generation fluoroquinolones have enhanced Gram-positive activity...

Neurotrophic keratitis

1 October 2014 | Sofia Rokerya | EYE - Cornea, EYE - General

The authors present an overview of the aetiology, diagnosis, current and future management options of neurotrophic keratitis. This is a degenerative corneal disease that occurs following the compromise of trigeminal innervation, leading to hypoesthesia and / or anaesthesia. The aetiology...

Adjunctive topical 5-FU vs. MMC for surgically excised, localised OSSN

1 October 2014 | Anjali Gupta | EYE - Cornea, EYE - General | OSSN, chemotherapy, ocular oncology, ocular surface tumours

Ocular surface squamous neoplasia (OSSN) comprises a range of dysplasia including corneal-conjunctival intraepithelial neoplasia and invasive squamous cell carcinoma. The traditional treatment for localised non-invasive OSSN has been surgical excision with or without intraoperative cryotherapy. Postoperative adjunctive topical chemotherapy significantly...

Blinking and driving

1 October 2014 | Khadijah Basheer | EYE - General

Spontaneous blinking is dependent on cognitive processes and is regulated by a central pacemaker that is highly sensitive to the attention demands and cognitive workload of the visual task in hand. There is evidence of a variability in the frequency...

Outcomes of corneal collagen crosslinking (CXL) in pseudophakic bullous keratopathy (PBK)

1 August 2014 | Sharmina Khan | EYE - Cornea, EYE - General

This was a retrospective non-comparative, interventional case series of 50 eyes in 50 patients with symptomatic PBK who underwent CXL (epithelium-off). Central corneal thickness (CCT), pain score, best corrected visual acuity (BCVA), and corneal transparency were recorded at baseline; at...

Topography based keratoconus progression after corneal collagen cross-linking

1 August 2014 | Sharmina Khan | EYE - Cornea, EYE - General

Case 1 describes a 35-year-old man with progressive keratoconus (PK). His best corrected visual acuity (BCVA) was right 20/80 (-5.25/-7.75 x 85) and left 20/20 (+4.75/-5.00 x 90). His Ks were right 36.32/48.02 D and 41.15/46.41 D. Right central cornea...

Pterygium ocular surface temperature

1 August 2014 | Khadijah Basheer | EYE - Cornea, EYE - General

This prospective study investigated the ocular surface temperature in patients with pterygia compared to those with dry and healthy eyes respectively. Previous studies have shown that patients with dry eyes show a significant decrease in ocular surface temperature on sustained...

Allergic conjunctivitis evaluation by thermography

1 August 2014 | Bheemanagouda Patil | EYE - Cornea, EYE - General

Thermography is a non-invasive imaging technique, which uses infrared radiation reflected from an object to estimate the temperature of the object. This paper evaluates the use of thermography to assess allergic conjunctivitis objectively, by using an instrument called ocular surface...

Effect of single intravitreal injection of bevacizumab on contrast sensitivity in patients with central retinal vein occlusion

1 August 2014 | Bheemanagouda Patil | EYE - Cornea, EYE - General

Central retinal vein occlusion is the second most common retinal vascular disorder after diabetic retinopathy. There are many studies reporting the efficacy of intravitreal anti-VEGF injections for macular oedema secondary to retinal vein occlusions. This paper looks at the contrast...

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