Likelihood of developing multiple sclerosis after optic neuritis diagnosis
3 April 2024
| Jonathan Chan
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EYE - Neuro-ophthalmology
Optic neuritis (ON) is a relatively common cause of acute optic neuropathy in young patients which often presents as the first sign of multiple sclerosis (MS). There is a lack of evidence around the factors that are associated with the...
A case series of electroretinography findings in visual snow syndrome
3 April 2024
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors present a case series of individuals referred to an electroretinography (ERG) lab for assessment due to abnormal vision symptoms, over a two year period. Cases with visual snow syndrome (VSS) or isolated visual snow (VS) were included. All...
Pilot trial of Fluoxetine for post-stroke homonymous hemianopia
3 April 2024
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors present a pilot randomised placebo controlled double blind trial assessing 20mg fluoxetine once daily for 90 days versus placebo in stroke survivors with isolated homonymous hemianopia. Exclusion criteria were extensive in terms of pre-existing ophthalmic or neurologic disease,...
The evolution and visual prognosis of glial proliferation of different grades after macular hole surgery
3 April 2024
| Sofia Rokerya
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EYE - Neuro-ophthalmology
This retrospective research study aimed to investigate the evolution of glial proliferation of varying grades after successful idiopathic macular hole repair and its effects on foveal microstructure and best-corrected visual acuity (BCVA). Two-hundred and two eyes were enrolled in this...
Comparison between findings in ‘active’ or ‘healed’ giant cell arteritis
29 March 2024
| Claire Howard
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EYE - Neuro-ophthalmology
Giant cell arteritis (GCA) is the most common systemic vasculitis in older people and can cause devastating sight loss if untreated. Temporal artery biopsy is often relied upon for diagnosis by ophthalmologists, with a positive biopsy result indicating whether the...
Referral patterns and pathways for intracranial hypertension
29 March 2024
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors present a retrospective case review of individuals with suspected raised intracranial pressure (ICP) over a 12-month period a single tertiary neuro-ophthalmology centre. Cases were categorised into four groups based on examination by neuro-ophthalmology; 1) referred after identification of...
Relationship between diabetic retinopathy and cerebrovascular reactivity changes
1 March 2024
| Claire Howard
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EYE - Neuro-ophthalmology
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Cerebral vasomotor reactivity, breath-holding index, diabetes mellitus, diabetic retinopathy, transcranial Doppler ultrasound
Cerebral micro-angiopathy caused by diabetes can manifest itself as an impairment in cerebrovascular reactivity. Transcranial doppler ultrasound (TCD) is a cost-effective and non-invasive way to measure the cerebrovascular reactivity. This study aimed to assess the relationship between the grade of...
Comparison of thrombolysis and conservative management in acute retinal ischaemia
1 March 2024
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors present a retrospective cohort study of individuals presenting with acute, painless, monocular vision loss and diagnosed with acute retinal ischaemia. Reasons for exclusion were iatrogenic aetiology, transient vision loss, missing initial visual acuity data, more than 16 hours...
Do occult neuroretinitis and non-arteritic anterior ischaemic optic neuropathy differ in presentation?
6 February 2024
| Claire Howard
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EYE - Neuro-ophthalmology
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Occult, differentiating, neuroretinitis, non-arteritic anterior ischaemic optic neuropathy, optical coherence tomography
This study evaluates differences between neuroretinitis and non-arteritic anterior ischaemic optic neuropathy (NAAION) in terms of patient demographics, clinical presentation, and optical coherence tomography (OCT) findings. Medical records of patients with a final diagnosis of occult neuroretinitis or NAAION were...
A review of neuro and retinal imaging findings in Alzheimer’s disease
6 February 2024
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors present a systematic review with the aim of assessing the relationship between retinal and cerebral changes in Alzheimer’s disease (AD), mild cognitive impairment and pre-clinical AD. A total of 23 articles met the inclusion criteria of the review,...
A review of the risk of nonarteritic anterior ischaemic optic neuropathy post-cataract surgery
2 February 2024
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
A systematic review and meta-analysis are presented with the aim of assessing whether cataract surgery increases the risk of non-arteritic anterior ischaemic optic neuropathy (NAION) and identify potential predictors of risk. The search strategy components are outlined in detail. A...
The expanding spectrum of idiopathic intracranial hypertension
2 February 2024
| Ivan Yip
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EYE - Neuro-ophthalmology
This is a review article from a tertiary centre in Atlanta, US. With rising obesity rates and increasing access for MRI scans there has been a large increase in patients requiring an urgent papilloedema check with incidental findings on MRI...
