Trabeculectomy for normal tension glaucoma
1 June 2016
| Jonathan Chan
|
EYE - Glaucoma
This is a retrospective consecutive, non-comparative case series of 131 eyes of 98 patients undergoing trabeculectomy between 2007 and 2013 in a normal tension glaucoma (NTG) clinic. Assessment of the clinical outcomes include intraocular pressures (IOP) reduction, bleb formation, final...
Update on primary angle closure glaucoma
1 June 2016
| Bheemanagouda Patil
|
EYE - Glaucoma
This review article considers primary angle-closure glaucoma which is responsible for half of glaucoma-related blindness worldwide. Angle closure is characterised by appositional contact between the iris and trabecular meshwork. It tends to develop in eyes with shallow anterior chambers, anteriorly...
A population based follow-up study on pseudoexfoliation and cataract surgery
1 April 2016
| Bheemanagouda Patil
|
EYE - Glaucoma
n association between pseudoexfoliation (PEX) and cataracts has been shown in many previous studies. Recently, the Australian Blue Mountains Eye Study, using the Wisconsin Cataract Typing and Grading System, observed an increased prevalence of nuclear cataract in eyes with PEX....
Aflibercept for the treatment of neovascular glaucoma
1 April 2016
| Anjali Gupta
|
EYE - Glaucoma
The aim of this study was to investigate initial results regarding the treatment of neovascular glaucoma (NVG) with intravitreal aflibercept. NVG is classified into stages 0-3. In stages 1 and 2, abnormal vessel proliferation is seen with or without elevated...
Anterior segment OCT predicts gonioscopic angle closure
1 February 2016
| Brian Ang
|
EYE - Glaucoma
This is a prospective observational study of 342 subjects over four years. Sixty-five were controls who had open angles both on gonioscopy and AS-OCT, while 277 had open angles only on gonioscopy but iridotrabecular contact (ITC) on AS-OCT (one to...
RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions
1 February 2016
| Wai Siene Ng
|
EYE - Glaucoma
This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...
Prostaglandin-associated periorbitopathy
1 February 2016
| James Hsuan
|
EYE - Glaucoma
This is a masked study of 33 patients who had been taking a prostaglandin analogue in one eye only for at least a year, to look for signs of prostaglandin-associated periorbitopathy (PAP). The investigators devised a new grading system to...
Phaco-ECP vs. Phaco alone to treat glaucoma
1 December 2015
| Anjali Gupta
|
EYE - Glaucoma
This retrospective review compared combined phacoemulsification and endoscopic cyclophotocoagulation (phaco-ECP) to phaco alone in patients with mild to moderate glaucoma. Outcome measures included cumulative full and qualified success survival, postintervention IOP and ocular anti-hypertensive medication reduction. Full success was defined...
Relationship between nocturnal intraocular pressure elevation and diurnal intraocular pressure level in NTG patients
1 October 2015
| Wai Siene Ng
|
EYE - Glaucoma
This group studies Korean normo-tension glaucoma (NTG) patients over a 24-hour period to assess if there was a relationship between nocturnal intraocular pressure (IOP) and diurnal IOP. They have previously suggested differences in diurnal IOP may have varying mechanisms of...
Effect of change in retinal nerve fibre layer thickness on quality of life in patients with glaucoma
1 October 2015
| Lona Jawaheer
|
EYE - Glaucoma
The authors investigated the relationship between structural changes in glaucoma (retinal nerve fibre layer (RNFL) thickness) and quality of life (as measured by the NEI VFQ-25 questionnaire) over a period of time. Two hundred and sixty eyes of 130 patients...
Comparison of methods of central corneal thickness measurement in glaucoma
1 October 2015
| Jaya Myneni
|
EYE - Glaucoma
This prospective study was done to compare the accuracy and reproducibility of central corneal thickness measured by hand-held and disc-mounted ultrasound pachymeter in glaucoma patients. Sixty-five patients were included in the study. Patients with corneal diseases, corneal astigmatism >3 diopters...
Sustained elevation of extracellular ATP in chronic glaucoma
1 August 2015
| Wai Siene Ng
|
EYE - Glaucoma
Although adenosine 5′-triphosphate (ATP) release from retinal neurons and astrocytes has been demonstrated in short-term increases in intraocular pressure (IOP); such as in aqueous humor of humans with primary acute angle closure glaucoma, the response in chronic IOP elevation was...
