Large series profiling skew deviation

A retrospective notes review was completed for patients identified as having skew deviation. The authors outline their exact definition of skew deviation within the methods of the paper. One hundred and fifty-seven patients were identified, it is not clear over...

MRI characteristics of NMO, MOG and MS-related ON

This review article examined differences of MRI appearances that can help clinicians assess and manage these important neuro-ophthalmic disorders. It also examined the role of optic nerve MRI as a prognostic indicator in acute optic neuritis (ON). The major findings...

Diagnostic accuracy of enhanced depth imaging OCT in children

The authors present the findings of a retrospective cross-sectional case series. Cases were identified using a treatment register having been evaluated in a set one-year period. Two ophthalmologists acted as masked image examiners for enhanced depth imaging optical coherence tomography...

Validity of coding in neuro-ophthalmology within large administrative datasets

A systematic review of validation studies of the International Classification of Disease (ICD) coding system, ICD-9 and ICD-10 is presented by the authors. Three searches were conducted based on three concepts, firstly health administration claims and ICD codes, secondly diagnostic...

The effect of caffeine on pupil size and accommodation

Twenty-two young and healthy participants were recruited in this study. The authors showed that pupil size increased as a result of caffeine consumption. A more stable (lower variability of accommodation) accommodative response (AR) was induced by caffeine intake, whereas the...

Long-term follow-up of OPGs in neurofibromatosis type 1

This retrospective observational case series reports outcomes of children followed-up for at least 10 years with optic pathway glioma (OPGs) related to neurofibromatosis type 1 (NF1) between January 1985 and July 2007. They observed 45 children for a mean of...

Anterior ischaemic optic neuropathy post cataract surgery

This retrospective population-based cohort study assessed whether there was an increased incidence of anterior ischaemic optic neuropathy (AION) post cataract surgery compared to patients that had not had cataract surgery. They reviewed the notes of all patients diagnosed with AION...

Switchover study from Botox to Xeomin for facial dystonia

This study carried out in the UK compared the clinical effectiveness and efficiency of switching patients from Botox® injections to Xeomin®. This was carried out in 20 essential blepharospasm, 12 hemifacial spasm and six aberrant facial nerve regeneration patients. Patients...

Unique case of steroid-induced intraocular pressure spike causing NAION

The literature describes previous cases of nonarteritic anterior ischaemic optic neuropathy (NAION) following rapid rises in intraocular pressure (IOP) leading to reduced optic nerve head perfusion and disruption. This is commonly following ophthalmic procedures, acute glaucoma or steroid eye drops....

Effects of idiopathic intracranial hypertension on the optic nerves

The authors review the latest evidence regarding how the optic nerves are affected by idiopathic intracranial hypertension (IIH), possible pathophysiology and methods of assessment. IIH is described as a clinical syndrome of raised intracranial pressure of unknown aetiology. A systematic...

Relationship between intraocular pressure and optic nerve damage in optic nerve drusen

The authors present a retrospective study exploring the relationship between intraocular pressure (IOP) and optic nerve damage in patients with optic nerve drusen. The aim was to evaluate if patients with normal ocular pressure at the time of optic nerve...

A novel way to distinguish between types of anterior ischaemic optic neuropathy

The authors evaluate the monocyte to high-density lipoprotein (HDL) ratio (MHR) in patients with arteritic and non arteritic anterior ischaemic optic neuropathy (A-AION / NA-AION). A distinction between the two types of AION is essential to begin appropriate treatment, which...