Journal Reviews
G-CSF intravitreal injections for NAION: a pilot study
In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...
Long-term use of botulinum toxin for hemifacial spasm and blepharospasm
The authors conducted a retrospective review of clinical / procedure documentation for consecutive blepharospasm (BEB) and hemifacial spasm (HFS) patients undergoing treatment with onabotulinum toxin A (Botox) in one clinic setting over the past 20 years. They report on the...
Case reports of ‘ictal lid saccades’ and ‘ictal blinks’
The authors present two cases of lid movements with discrete physiology and propose the terms ‘ictal lid saccades’ and ‘ictal blink’ to describe the movements seen. These two types of lid movement, blinks and saccades, have discrete kinematic properties and...
Lagophthalmos as a potential complication of COVID-19
Lagophthalmos is a condition associated with the inability to close the eyelids effectively, with the main cause being facial nerve palsy. The authors aimed to investigate whether lagophthalmos was associated with coronavirus infection (COVID-19) by comparing patients diagnosed with lagophthalmos...
A survey of neuro-ophthalmologists on use of corticosteroids in giant cell arteritis
While corticosteroids are the mainstay of treatment in giant cell arteritis (GCA), the type, dose, route and duration of treatment remains controversial. The authors surveyed 180 neuro-ophthalmologists on their use of this treatment via email in a two-month period. Results...
A retrospective medical notes review in patients with poor vision due to NAION
Very severe visual loss (hand movements or less) is typical of arteritic anterior ischaemic optic neuropathy (AION) and relatively rare in non-arteritic AION (NAION). This study aimed to report the frequency of very poor visual acuity (VA) in NAION. The...
Long-standing flattening effects on the globe following spaceflight
Posterior globe flattening has been well-documented in astronauts both during and after long-duration spaceflight (LDSF). This globe flattening is thought to be due to the disc centred anterior forces created by elevated volume and / or pressure within the optic...
A case presentation of morning glory disc anomaly and peripapillary staphyloma
The purpose of this paper is to present a case of an 18-month-old girl initially presenting with strabismus. Fixation of the affected eye was intermittent with a relative afferent pupillary defect. A fundus photography of the affected left eye showed...
Differences between ages and onset in functional network changes associated with reading Braille
Visual impairment affects learning ability, speed and accuracy required for reading, writing and learning memory in terms of educational performance. Braille training requires decoding of simple dots into meaningful words and sentences. The objectives of this study were to evaluate...
Unusual case presentation of arteritic anterior ischaemic optic neuropathy
The authors present a single case of an 84-year-old man with arteritic anterior ischaemic optic neuropathy, but with unusual features on temporal artery biopsy. He presented with a three-day history of sudden onset of loss of vision in his right...
Detection of post stroke visual impairment in variety of cohorts
The Impact of Visual Impairment after Stroke (IVIS) study introduced a standardised vision assessment protocol across three acute stroke units in the northwest of England, with a similar demographic population (predominantly white British). The study reported similar rates of visual...
Detailed overview of diplopia causes and outcomes for a single tertiary care centre
The purpose of this study was to study the aetiology, progression and outcome in patients with binocular diplopia presenting to the ophthalmology department of a tertiary care centre in India. The study had a prospective observational design where all patients...
