Using a driving simulator to explore the effect of visual field loss from optic disc drusen

The purpose of this study was to compare driving simulator performance of participants with visual field loss (VFL) from optic disc drusen (ODD) with a normally sighted control group and a group of individuals with glaucoma. Data on performance and...

Can coenzyme Q10 have a protective role in ethambutol-induced retinal ganglion cell toxicity

Tuberculosis (TB) is one of the most prevalent infectious diseases, especially in developing or low- income countries. Ethambutol is a widely used drug to treat TB. Ethambutol can cause visual disturbance including ethambutol toxic optic neuropathy (ETON). ETON is one...

Sub-clinical detection methods in multiple sclerosis

Visually symptomatic multiple sclerosis (MS) provides only part of the required information to assist in understanding the disease. Recently, researchers have concentrated their efforts on diagnosing MS cases in the subclinical period. The aim of this paper was to assess...

Case report review of children with septo-optic dysplasia and optic nerve hypoplasia

Septo-optic dysplasia (SOD) and optic nerve hypoplasia (ONH) cause congenital visual impairment. Their aetiology is mostly unknown. The authors aim was to investigate the prevalence of specified ophthalmological features in patients with these disorders. These features included impaired visual acuity,...

Natural history of idiopathic intracranial hypertension depending on incidental or symptomatic presentation

The authors present a large retrospective review cohort of consecutive patients diagnosed or presumed idiopathic intracranial hypertension (IIH) over a three-year period at a single tertiary centre. Patients on medication with a known aetiology for IIH were excluded. The cohort...

Patterns of binocular diplopia in giant cell arteritis (GCA)

Giant cell arteritis (GCA) is a granulomatous vasculitis that targets medium and large sized vessels. Binocular diplopia has been reported in a small number of patients with visual manifestations of GCA. It can be caused by ischaemia in any segment...

Prognosis prediction using clinical findings for fourth nerve palsies

The authors present a retrospective review of a cohort of patients diagnosed with fourth cranial nerve palsy with more than six months follow-up, over a 10-year period at a single centre. Thirty-five patients were included in the study, and spilt...

Amyotrophic lateral sclerosis (ALS): what happens to eye movements?

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper motor neurons of the corticospinal tract and lower motor neurons in brainstem nuclei and the anterior horn of the spinal cord. Limited literature is available on abnormal ocular movements in...

Retrospective review of visual outcomes in Idiopathic intracranial hypertension (IIH)

Idiopathic intracranial hypertension (IIH) is a clinical syndrome characterised by headache and papilloedema that can lead to significant visual morbidity. IIH is diagnosed by the modified Dandy criteria, which include normal neuroimaging and cerebrospinal fluid (CSF) composition, high CSF opening...

Does religious fasting affect intraocular pressure or retinal parameters?

Nearly one billion Muslims fast every year during the month of Ramadan. Due to the difference between the lunar and solar calendars, religious fasting time can range from 11 to 17 hours per day. This prolonged abstinence from food and...

Do patients with prolactinomas using dopamine agonist drugs have autonomic dysfunction?

This prospective study aimed to determine whether there is autonomic dysfunction in patients with prolactinomas using dopamine agonist (DA) drugs by measuring static and dynamic pupillary responses using an automatic pupillometric device.Included were 25 eyes from 25 patients who were...

Visual prognosis in Irish Leber’s hereditary optic neuropathy

Leber’s hereditary optic neuropathy (LHON) is an inherited optic neuropathy This paper presents a retrospective review of clinical data from patients with LHON presenting to an Irish tertiary referral ophthalmic hospital. Clinical and genetic characteristics were assessed for useful biomarkers...