Journal Reviews
Bitemporal hemianopsia as a result of ethambutol toxicity
The authors present six cases of visual loss in patients treated with ethambutol for mycobacterium avium complex, including four patients with bitemporal hemianopsia. Two additional patients were undergoing glaucoma monitoring and developed visual field defects with ethambutol treatment, which recovered...
Case report of Leber hereditary optic neuropathy (LHON)
This case report presents a 74-year-old male patient who developed LHON, with a previous diagnosis of bilateral macular holes. LHON occurs predominantly in healthy young men and onset in older age ranges increases the likelihood that the patient will have...
Review of non-arteritic anterior ischaemic optic neuropathy
This article reviews the risk factors, clinical presentation and therapies that have been investigated for non-arteritic anterior ischaemic optic neuropathy (NAAION). Additionally, it provides an update from recent rodent and primate models, offering a new insight into the pathophysiology of...
Leber’s hereditary optic neuropathy: from lab to clinic
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...
Comparison of treatment for hemianopia following stroke
The authors report the screening process and recruitment figures for a randomised controlled trial comparing interventions for post stroke homonymous hemianopia. Interventions included Fresnel prisms, visual search training and standard care (information only). Primary outcome measure was the change in...
Characteristics and incidence of sixth nerve palsy in children with intracranial hypertension
The authors report the incidence and characteristics of sixth cranial nerve palsy in paediatric patients with intracranial hypertension. A retrospective review of records was performed in central Ohio over a three year period and nine children were found to have...
An unusual third nerve palsy case report
The authors present the unusual case of a 23-year-old male presenting to hospital with right eye pain, right upper eyelid ptosis, blurred vision and diplopia, developing immediately after a penetrating injury to his right upper eyelid. On assessment he was...
An unusual case of partial oculomotor nerve palsy
The authors present an unusual case of intra-axial oculomotor nerve involvement due to midbrain infarction. The 65-year-old male patient presented with unilateral complete blepharoptosis and slight limitation of upgaze. Neurological examination revealed a complete ptosis of the left eyelid, slight...
Driving with the use of spectacle mounted telescopes (bioptics)
The authors discuss the current perspectives of spectacle mounted telescopes (bioptics) whilst driving among patients with visual impairment. The history, design and driving laws surrounding the use of bioptics is discussed in detail. In 1977, William Feinbloom developed a bioptic...
Retinal changes in Leber hereditary optic neuropathy
The objective of this study was to describe the changes in the retinal ganglion cell complex (GCC) relative to the retinal nerve fibre layer (RNFL) over time, in patients with Leber’s hereditary optic neuropathy (LHON). For this study, 21 patients...
Static subjective visual vertical (SVV) in the normal visual system
Graviception is the perception of a persons’ orientation relative to gravitational force. This can be measured by means of subjective verticals, which can be divided into three tests: subjective visual vertical (SVV), subjective postural vertical (SPV) and subjective haptic vertical...
Use of RAPDx device with optic nerve disease
The authors have previously reported on use of the RAPDx device for evaluating relative afferent pupillary defects (RAPD). RAPDx objectively determines the magnitude of RAPD by presenting light stimuli alternately to pairs of eyes with laterality. The parameters of amplitude...
