Prevalence of misdiagnosis of third nerve palsy by referring clinicians

The authors present a retrospective case review of new patient presentations to a neuro-ophthalmology clinic at two centres between 2014 and 2017. The electronic medical records were searched using the variety of terms for third nerve palsy. Referral for management...

New prognostic model for multiple sclerosis after optic neuritis presentation

The authors present a post-hoc analysis using the publicly available data set from the Optic Neuritis Treatment Trial. The Cox proportional hazards regression models were used to assess for associations between clinical and radiological variables and the development of clinical...

Test combination which could detect prodromal Alzheimer disease

The authors prospectively recruited a convenience sample of individuals aged over 65 and either with a diagnosis of mild cognitive impairment (MCI) due to Alzheimer disease or normal cognition. Other types of dementia and severe neurological conditions were excluded. All...

Care pathway to imaging delays for acute oculomotor nerve palsies

A retrospective chart review is presented with the aim of evaluating arterial imaging in cases of third nerve palsy. The study reviewed patients seen with a suspicion of or a final diagnosis of third nerve palsy over a seven-year eight-month...

Care journeys of patients with central retinal artery occlusion

The authors present a retrospective case note review of all adult patients referred for or diagnosed with central retinal artery occlusion (CRAO) to a single tertiary hospital over a 10½ year period. A total of 181 patients were included in...

Transient visual loss caused by crowded optic discs

The author presents four cases of transient visual loss (TVL) in young females (age range at presentation 14-22 years) with crowded optic discs. Patient demographics, investigations, medical and social histories are provided for all patients. A review of evidence for...

Assessment of slow and fast vergence in stroke survivors

The authors present the findings of a prospective cohort study. Three hundred and five stroke survivors were recruited consecutively. The following exclusion criteria were applied; aphasia, cognitive impairment, visual inattention, ocular motor nerve palsy and neuromuscular disease. Fifty age-matched controls...

Screening for visual processing deficits in dementia

The Queen Square Screening test for Visual Deficits (QS test) screens for changes in visual processing. It has never been formally validated as a single test. The test consists of a short booklet developed using remnant object and spatial perception...

Using optical coherence tomography angiography to detect MoyaMoya vasculopathy

Moyamoya (MM) disease is a chronic cerebrovascular disease that can lead to progressive stenosis of the terminal portions of the internal carotid arteries and their proximal branches. The authors carried out a cross-sectional cohort study to investigate vascular changes in...

Where along the vergence pathway is affected by Parkinson’s Disease?

The authors outlined three hypothesis for the effect Parkinson’s Disease has on blur- and disparity-driven vergence with reference to location within the vergence system that is affected to be tested in this prospective study. The study recruited 14 participants with...

G-CSF intravitreal injections for NAION: a pilot study

In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...

Long-term use of botulinum toxin for hemifacial spasm and blepharospasm

The authors conducted a retrospective review of clinical / procedure documentation for consecutive blepharospasm (BEB) and hemifacial spasm (HFS) patients undergoing treatment with onabotulinum toxin A (Botox) in one clinic setting over the past 20 years. They report on the...