Journal Reviews
A review of chromosome 9p21 POAG susceptibility locus
Primary open angle glaucoma (POAG) is a genetically complex disease and the overall phenotype is influenced by multiple traits including intraocular pressure (IOP), central corneal thickness and structural features of the optic nerve head. Therefore, genes affecting any of these...
Sleep positions and the effect on IOP
The authors describe a study to determine if sleeping at a 20 degree head up position decreases nocturnal IOP compared with lying supine in patients with and without glaucoma. They recruited 30 patients (60 eyes) 15 with glaucoma and 15...
Latanoprost in the treatment of congenital glaucoma
The aim of this study was to investigate the glaucoma control of latanoprost therapy in primary congenital glaucoma (PCG) and assess the factors affecting long-term outcome. Eighty-one eyes of 44 patients with PCG and 42 eyes of 29 patients with...
SLT short-term results
The aim of the study was to evaluate the risk of adverse effects and short-term results after 360 degrees selective laser trabeculoplasty (SLT) in glaucoma patients. The authors enrolled 64 eyes of 64 patients all who had poorly controlled primary...
Canaloplasty after failed trabeculectomy
The authors describe the technique of canaloplasty performed in five patients who had undergone previous trabeculectomy and under maximum tolerated medical therapy or insufficient intraocular pressure (IOP) control. Canaloplasty is described by the authors as “a nonperforating blebless technique derived...
A ciliary body tumour
The authors describe a case report of a 60-year-old woman found to have advanced angle closure glaucoma in her right eye and appositional closure of half of the left eye and no glaucoma. The patient had previously undergone two trabeculectomies...
Risk calculation variability over time in OHT
In this study the authors aimed to assess the variability of the well documented risk model from the Ocular Hypertension Treatment Study (OHTS) that identified higher intraocular pressure (IOP), older age, lower central corneal thickness (CCT), greater vertical cup-to-disc ratio...
RAPD in glaucoma screening
A study was conducted to investigate the relative afferent pupillary defect (RAPD) by swinging flashlight as a potentially useful screening test for glaucomatous optic neuropathy. The authors recruited 107 subjects with or without glaucoma from a clinic population. A medical...
Macular thickness and visual fields
The authors describe a comparison of spectral domain OCT with Humphrey visual fields (HVF) mean deviation (MD) and pattern standard deviation (PSD), examining the retinal thickness of the macula and circumpapillary retinal nerve fibre layer (RNFL) defects. Seventy-three subjects who...
Arterial stiffness and PEX
The authors describe a study of 25 newly diagnosed patients with pseudoexfoliation glaucoma (PEX) and 25 controls to evaluate carotid femoral pulse wave velocity (CF-PWV) values. The CF-PWV was assessed using a noninvasive device by measuring the pulse transmit time...
High myopes with POAG and IOP fluctuations
The authors describe a prospective study of 80 eyes of Chinese patients with primary open-angle glaucoma (POAG) on prostaglandin analogues to investigate if those who also have high myopia exhibit greater short-term intraocular pressure (IOP) fluctuations at resting conditions over...
Visual impairment in patients with glaucoma
This retrospective observational study assessed the prevalence of end-of-life visual impairment in patients with glaucoma. A total of 122 deceased patients followed for glaucoma were included and data was collected from patient notes. Sixty-one patients had open-angle glaucoma and 61...
