Are single IOP measurements adequate for estimating the effect of IOP lowering interventions?

The World Glaucoma Association recommends that, to assess the effect on intraocular pressure (IOP) of medication or surgery, the mean of multiple measurements of postoperative IOP is a better reflection of IOP than a single measurement of postoperative IOP. The...

Comparison of false-negative responses in glaucoma patients and normal observers

The authors compared false negative rates for full threshold (FULL) and Swedish Interactive Threshold Algorithm (SITA) standard automated perimetry in healthy control subjects and glaucoma patients. Twenty-four subjects underwent visual field testing of one eye five times within six weeks...

Beliefs and adherence to glaucoma treatment

The aim of the study was to determine adherence rates and beliefs about glaucoma and its treatment in white Americans, African Americans, white Australians and Singaporeans of Chinese descent. A cross-sectional study of 475 glaucoma patients using topical eye drops...

Brimonidine day and night time IOP

The authors describe a randomised double masked study of 29 participants with ocular hypertension (OHT) who either self-administered 0.2% brimonidine or placebo three times daily for six weeks. Patients were seen during day time and night time visits and had...

Hyphema after trabeculectomy with MMC

The authors retrospectively reviewed the medical records of consecutive patients with glaucoma who underwent trabeculectomy with mitomycin C between June 2005 and December 2010 to determine the risk factors for hyphema after surgery. Of the 420 patients, 104 (24.8%) had...

Bleb-related infection after mitomycin C trabeculectomy

The authors report on the results of the Collaborative Bleb-related Incidence and Treatment Study (CBIITS), which was a five year multi-centre prospective study designed to investigate the incidence of bleb-related infection following filtering surgery with mitomycin C. In this study,...

Effects of topical anaesthetic on intraocular pressure

This prospective interventional study assessed the effects of repeated intraocular pressure (IOP) using Goldmann applanation tonometry and applanation resonance tonometry in six volunteers. Previous literature supports IOP reduction using repeated applanation tonometry. Repeated IOP measures were taken alternately on 12...

A review of chromosome 9p21 POAG susceptibility locus

Primary open angle glaucoma (POAG) is a genetically complex disease and the overall phenotype is influenced by multiple traits including intraocular pressure (IOP), central corneal thickness and structural features of the optic nerve head. Therefore, genes affecting any of these...

Sleep positions and the effect on IOP

The authors describe a study to determine if sleeping at a 20 degree head up position decreases nocturnal IOP compared with lying supine in patients with and without glaucoma. They recruited 30 patients (60 eyes) 15 with glaucoma and 15...

Latanoprost in the treatment of congenital glaucoma

The aim of this study was to investigate the glaucoma control of latanoprost therapy in primary congenital glaucoma (PCG) and assess the factors affecting long-term outcome. Eighty-one eyes of 44 patients with PCG and 42 eyes of 29 patients with...

SLT short-term results

The aim of the study was to evaluate the risk of adverse effects and short-term results after 360 degrees selective laser trabeculoplasty (SLT) in glaucoma patients. The authors enrolled 64 eyes of 64 patients all who had poorly controlled primary...

Canaloplasty after failed trabeculectomy

The authors describe the technique of canaloplasty performed in five patients who had undergone previous trabeculectomy and under maximum tolerated medical therapy or insufficient intraocular pressure (IOP) control. Canaloplasty is described by the authors as “a nonperforating blebless technique derived...