Journal Reviews
Effects of ML4 on the eye
Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...
Surgical management and review of congenital inferior rectus dysgenesis
Three cases are presented of congenital inferior rectus (IR) dysgenesis causing hypertropia. Case 1 was a two-year-old female with intermittent vertical strabismus of 20PD and -2 limitation on depression, worse in abduction. MRI imaging showed a hypoplastic IR. Following surgery,...
Proof of concept for using aqueous humour to detect retinoblastoma variant
A proof of concept study is presented with the aim of assessing the feasibility of using aqueous humour surrogate marker for tumour tissue for identifying retinoblastoma RB1 variant. Three children undergoing enucleation for retinoblastoma were recruited from a single centre....
Long-term improvement of stereopsis in intermittent refractive esotropia
This was a retrospective study to review the records of patients with refractive accommodative esotropia (RAET) to determine long-term stereoacuity (SA) improvement in those that showed initial poor or no stereopsis. The study included 79 patients; 54% male and mean...
ROP risk factors
The purpose of this study was to evaluate the incidence and risk factors for retinopathy of prematurity (ROP) in two neo-natal units, and included a sub-analysis of infants with gestational age (GA) of ≥28 weeks. A retrospective review was undertaken...
Outcomes of adult new-onset strabismus presenting acutely
This study evaluated causes, neuroimaging rates and results, and clinical courses of adults presenting to an ophthalmology emergency department with diagnosis of new-onset strabismus. This was a retrospective study of 557 adults (54.8% male) with mean age of 57.3 ±16.7...
Significant associations to presence of significant retinal haemorrhages in suspected child abuse
The authors aimed to extract statistically significant associations between non-ocular clinical and diagnostic imaging findings and the presence of significant retinal haemorrhages, and then develop an evidence-based screening algorithm to determine when to consult an ophthalmologist in suspected child abuse...
Comparison of outcomes of bilateral cataract surgery across different age groups
The authors present a retrospective records review of children who had bilateral cataract surgery between the ages of two and seven years of age over a 23-year period. Children with other ocular pathology and prior surgery were excluded. A minimum...
Possible mechanism for infant development of secondary glaucoma
The authors consider published evidence with regard to potential causative mechanisms for secondary glaucoma that follows infant lensectomy. They review clinical and laboratory studies. The mechanism they propose is that the original lensectomy surgery releases immature anterior lens cells into...
Comparison of nylon versus polyglactin sutures
The purpose of this study was to compare postoperative complications between incision closure by nylon suture and polyglactin suture in paediatric cataract surgery. This was a prospective single-centre non-randomised study of 82 eyes (41 children) with median age of four...
Change in psychosocial, quality of life and anxiety after strabismus surgery
The authors aimed to define the impact of surgical correction on psychiatric problems, health-related quality of life and anxiety levels in children and their parents. This was a cross-sectional study of 39 children with strabismus and their parents. All children...
Sensorimotor outcomes following paediatric ocular trauma
A retrospective assessment of sensorimotor outcomes was conducted in paediatric patients after ocular trauma to evaluate potential predictors of poor outcome including time of treatment deprivation, Paediatric Ocular Trauma score (POTS) and patient characteristics. The review was from 2006-2020 and...
