Maintenance therapy for CMV endotheliitis

Cytomegalovirus (CMV) has been associated with corneal endotheliitis, leading to endothelial cell loss and corneal decompensation. CMV corneal endotheliitis recurrence can affect between 5-60% of eyes after cessation of anti-CMV therapy. Each recurrence of endotheliitis has a detrimental effect on...

Outcomes of primary and repeat DSAEKs

Retrospective analysis of results following primary and secondary descemet stripping automated endothelial keratoplasty (DSAEKs), carried out in Villa Serena-Villa Igea Private Hospitals in Italy, showed that primary and secondary DSAEK surgery result in similar visual outcomes, refractive errors and endothelial...

Risks factors for graft preparation failure in DMEK

Diabetes mellitus (DM) makes it more difficult to prepare descemet membrane epithelial keratoplasty (DMEK) grafts due to the ‘stickiness’ of Descemet’s membrane. This retrospective study examined a classification system, where donors were scored points according to their DM related risk...

Conjunctivochalasis and aqueous tear deficiency – which one causes symptoms?

This review sought to determine whether conjunctivochalasis (CCh) obliterates the fornix tear reservoir and thus mimics aqueous tear deficiency (ATD). Patients were divided into two groups, with aqueous tear deficiency (CCh +ATD) or without (CCh –ATD), based on results of...

Penetrating keratoplasties in infants

This retrospective review looked at endothelial cell counts (ECC) following penetrating keratoplasties (PKP) performed in infants within the first year of their life. One hundred eyes of 71 patients had their first PKP during the study period (1998-2013). In 30%...

Acanthamoeba ability to adhere to different contact lenses

This study tested ability of Acanthamoeba lugdunensis trophozoites to adhere to silicon hydrogel contact lenses (SHCL) and how this is influenced by different multipurpose contact lens solutions (MPS). Three generations of SHCL were tested: first generation – Air Optix, second...

Dry eyes after photorefractive keratoplasty

This study examined changes in tear break up time (TBUT), Schirmer test, tear osmolarity and dry eye questionnaire (OSDI) score from prior to photorefractive keratoplasty (PRK), to two months and four months postoperatively. Fifty eyes of 25 patients were examined....

Treatment of Sjogren’s Syndrome dry eye in mouse model

Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...

Central corneal and epithelial thickness measured by Fourier domain OCT

This study examined intraobserver and interobserver reproducibility of corneal thickness (CT) and epithelial thickness (ET) measurement of Fourier domain OCT (RTVue) in 23 healthy volunteers. RTVue is capable of producing 26,000 A scans per second with depth resolution of 5µm....

Corneal tattooing as treatment for bullous keratopathy

This retrospective study looked at differences in epithelial smoothing in patients with bullous keratopathy (BK) undergoing either corneal tattooing or anterior stromal puncture (ASP). Both procedures were carried out for symptomatic relief in eyes with poor visual potential. Chinese ink...

DALK as an early therapeutic option for Acanthamoeba keratitis

Eleven patients with Acanthamoeba keratitis (AK) were treated by early therapeutic deep anterior lamellar keratoplasty (DALK). All surgeries were performed in patients who had no response to standard medical therapy of chlorhexidine gluconate, propamidine isethionate and neomycin sulphate, within 10-15...

Familial Mediterranean Fever and keratoconus

This retrospective case control study was conducted in the Genetic Diagnostic Centre in Turkey. It examined the prevalence of keratoconus in two groups; patients with Familial Mediterranean Fever (FMF) and age matched controls free of FMF, who were tested for...