Multidrug-resistant keratitis: challenging yet manageable

This is a retrospective review of all patients’ records from a tertiary referral centre in India from January 2018 to December 2019, who had corneal scrapings for direct smear and culture sensitivity. Those cases where the organisms were diagnosed to...

Patients prefer vision from lasik than from smile in a contralateral-eye trial

This prospective, randomised, single surgeon, contralateral-eye clinical trial compared the results in myopic patients undergoing wavefront-guided femtosecond laser in situ keratomileusis (LASIK) in one eye and small-incision lenticule extraction (SMILE) in the fellow eye. The patient-reported outcomes with laser in...

Depth and width of corneal wounds post corneal foreign body removal

This was a prospective study of 63 eyes of 63 patients undergoing corneal foreign body (FB) removal with a 27G needle at the slit-lamp; 96.8% of the patients were men with mean age 35.8 ±11.0 years. Regarding location of FBs,...

Real-world experience of using ciclosporin-A 0.1% in the management of ocular surface inflammatory diseases

This is a retrospective study of patients with ocular surface inflammatory diseases (OSIDs) treated with IKERVIS in a single centre between 2016 to 2019 with at least six months follow-up. Clinical outcome was defined as successful (resolved or stable disease),...

Management of ocular surface disease

This is a retrospective study of patients with ocular surface disease (OSIDs) treated with IKERVIS in a single centre between 2016 to 2019 with at least six months follow-up. Clinical outcome was defined as successful (resolved or stable disease), active...

Bacterial keratitis through the window of the known unknowns

This review article provides an up-to-date summary of current challenges in research and management of bacterial keratitis. The authors highlight that there is no current agreement on the criteria that should define bacterial keratitis; the role of investigation is unclear,...

Human leucocyte antigen association of patients with Stevens-Johnson syndrome in Han Chinese

This is a retrospective study of the human leucocyte antigen (HLA) polymorphism pattern of cold medicine-induced patients with Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) (n=33) and 98 control patients recruited between 2016-2017 in Taiwan. Severe ocular complications (SOC) was...

BESTi: a new index to detect subclinical keratoconus

In this multicentre, case-control study, the authors develop a new index, named Boosted Ectasia Susceptibility Tomography Index (BESTi), to detect early cases of keratoconus. This index was derived from multiple logistic regression analysis of 22 variables of tomography scans. The...

Does pregnancy cause progression of keratoconus in previously cross-linked corneas?

This is a prospective study involving 24 eyes of 19 patients with stabilised or regressed keratoconus after a successful accelerated cross linking (A-CXL) treatment. Patients were recruited at a routine follow-up visit in the first month of their pregnancy. The...

Endothelial keratoplasty (EK) with anterior chamber intraocular lens (ACIOL) versus secondary posterior chamber lens (PCIOL)

This is a retrospective study of 82 eyes (23 ACIOL, 59 PCIOL) with a history of either pseudophakic (PBK) or aphakic (ABK) bullous keratopathy, who had descemet stripping automated endothelial keratoplasty (DSAEK) with retained or secondary ACIOL, or DSAEK with...

Second primary tumours after sebaceous carcinoma

This is a study investigating the risk of developing a second primary malignancy in patients previously diagnosed with eyelid sebaceous cell carcinoma. The records of 559 patients who were diagnosed with sebaceous cell carcinoma between 2000 and 2016 were reviewed,...

Effects of market competition on the price of topical eye drops in the US

The authors retrospectively examined the relationship between the number of Federal Drug Administration (FDA)-approved manufacturers and the price change of generic and branded topical eye medications based on the formulations listed in the FDA Orange Book and the National Average...