Journal Reviews
Lacquer cracks
The purpose of this Japanese study was to analyse the morphologic features and natural progression patterns of lacquer cracks (LC). The presence of linear hyperfluorescence on the fundus fluorescein angiography (FFA) was used as the standard for diagnosing the presence...
Subthreshold micropulse laser in BRVO
The purpose of this retrospective, consecutive, single-centre, non-randomised, and case-control study was to verify the therapeutic effects and safety of oedema (from branch retinal vein occlusion (BRVO)) recurrence suppression effect using 577-nm subthreshold micropulse laser photocoagulation (SMLP) in combination with...
DRIL after macular oedema treatment in BRVO
The authors report the analysis of a single-site, retrospective, cross-sectional study to evaluate the association between disorganisation of the retinal inner layers (DRIL) and visual acuity (VA) after anti-VEGF treatment for macular oedema (MO) due to branch retinal vein occlusion...
Vitrectomy in retinal detachment associated with choroidal detachment
Hypotony, posterior retinal breaks, longer axial lengths and total retinal detachments (RD) are risk factors for development of RD associated with choroidal detachment (RRDCD). This study retrospectively analysed the anatomic outcomes and prognostic factors of vitrectomy in 175 patients with...
Macular atrophy and choriocapillaris nonperfusion
This Japanese study compared the choriocapillaris (CC) nonperfusion area as measured on OCTA with areas of macular atrophy (MA) measured by fundus autofluoresence (FAF). A total of 44 eyes were assessed (31 were treated with anti-VEGF alone and 13 had...
Is pre-eclampsia / eclampsia a risk factor for non-infective uveitis?
This population based retrospective matched cohort study was the first of its kind to suggest an association between preeclampsia / eclampsia (PEE) and non-infective uveitis (NIU). They used the Longitudinal National Health Insurance database in Taiwan to assess 2073 post-delivery...
Multimodal imaging in wet AMD
This novel study set out to determine grader agreement levels of various retinal imaging techniques, commonly used in the diagnosis of wet age-related macular degeneration (AMD). Images from 52 eyes were by examined by two different observers. All images were...
CMV assessment
This is a retrospective, cross-sectional review of medical records from a consecutive series of patients with AIDS-related cytomegalovirus (CMV) retinitis who were examined at five HIV disease clinics in Yangon, Myanmar, in November 2006. All patients with CD4+ T lymphocytes...
VKH outcomes with pulse IV steroids
This is a retrospective review of clinical case notes records of 111 Vogt-Koyanagi-Harada (VKH) patients between 1999 and 2015 from a single centre in Tokyo, Japan. The mean age at presentation was 41 years and the median follow-up period was...
Aflibercept treatment in polypoidal choroidal vasculopathy
The authors present a study to evaluate the anatomical and functional efficacy of aflibercept intravitreal (IVT) as a monotherapy in polypoidal choroidal vasculopathy (PCV) in a Caucasian population treated with initial three-monthly aflibercept IVT, followed by a bimonthly regimen for...
Is serum ACE useful in diagnosing sarcoidosis in uveitis patients?
This retrospective clinical notes review assesses whether serum angiotensin converting enzyme (ACE) is useful in the diagnosis of sarcoidosis in patients presenting with uveitis. There were 1035 consecutive subjects presenting with uveitis as part of baseline investigations had a serum...
Do bilateral same day intravitreal injections increase the risk of endophthalmitis?
This large retrospective cohort study reviewed all patients who had bilateral intravitreal anti-vascular endothelial growth factor (VEGF) injections between April 2012 and August 2017. There were 101,932 procedures performed in 5890 patients. The two most common indications for injections were...
