Journal Reviews
OCTA in diabetic macular oedema treated with intravitreal aflibercept (DOCTA Study)
Central vision loss due to diabetic macular oedema (DME) can be attributed not only to presence of the macular oedema itself but also, in some cases, to alterations of the foveal avascular zone (FAZ). The DOCTA trial was a longitudinal,...
All you need to know about PIC
This is a review article of punctate inner chorioretinopathy (PIC). The authors detail the epidemiology and clinic presentation of the disease. They recognise the challenge of an accurate diagnosis due to its resemblance to other posterior uveitic entities. Multimodal imaging...
The compendium to clinical evidence in DMO treatment
This review article summarises the current evidence base in the treatment options for diabetic macular oedema (DMO). The authors have included many real-world data studies that provided valuable insights into the optimal management of DMO. The authors argue that these...
Macular pigment in relatives of AMD patients
Blue light causes photo-oxidative retinal injury and macular pigment (MP), with lutein, zeaxanthin and mesozeaxanthin as the main components, as a filter that protects the macula from this damage. Previous studies indicated that low levels of macular pigment optical density...
The potential of artificial intelligence and digital health in global eye health
This article provides an overview of the current landscape of artificial intelligence (AI) and digital health in global eye health. Tan, et al. note that though significant progress has been made in global eye health over the last few decades,...
Genetics counsellors in inherited retinal disease clinics
This is a questionnaire-based study from the USA of genetics counsellors with a primary role working within ophthalmology services. The purpose was to investigate the roles currently undertaken, to assess workload, and to acquire data on the experience of genetics...
Progression of macular atrophy in Stargardt disease
The authors present a study of a cohort of patients with genetically proven ABCA4 gene mutation related Stargardt disease. They aimed to quantify the effect of lesion location and topography on disease progression using fundus autofluorescence imaging. One hundred and...
Intravitreal Bevacizumab for the prevention of postoperative proliferative vitreoretinopathy in high-risk patients
This single- centre observational retrospective study was conducted to evaluate the effect of intravitreal injection of bevacizumab at the time surgery for rhegmatogenous retinal detachment (RRD) repair on postoperative proliferative vitreoretinopathy (PVR) in patients at high risk selected by laser...
Clinical predictors of proliferative sickle cell retinopathy
Sickle Cell Disease (SCD) is an inherited disorder resulting in production of Haemoglobin S (HbS), which aggregates in conditions of hypoxia, acidosis or hyperosmolarity. This leads to vascular stasis, thrombosis and ischaemia. The authors present a cross-sectional study (45 consecutive...
PRPF31-related retinitis pigmentosa and asymptomatic carriers
The authors present a study of 21 patients with variants in the PRPF31 gene classified as pathogenic or likely pathogenic. These variants are caused by autosomal dominant retinitis pigmentosa (RP-11). Between January 2020 and November 2021 patients underwent tests of...
Inverted internal limiting membrane flap vs internal limiting membrane insertion technique for large macular holes
This meta-analysis aimed to compare and evaluate the morphological and functional outcomes between the inverted internal limiting membrane (ILM) flap and ILM insertion techniques in the treatment of large macular holes (MHs). The primary outcome measures were defined by the...
Internal limiting membrane (ILM) peeling on blood flow in diabetic macula
This is a retrospective review of notes for diabetic patients with epiretinal membrane (ERM) who underwent surgery by the same surgeon. Nineteen had ERM peeling only, while the remaining 18 had both ERM and internal limiting membrane (ILM) peeling. The...
