Tocilizumab in Graves’ orbitopathy

This prospective European study looks at the response to tocilizumab in corticosteroid-resistant disease. Tocilizumab (TCZ) is a monoclonal antibody that competitively inhibits IL-6 binding to its receptor. Unlike teprotumumab, the advantage of TCZ is that it is already used within...

Complications of orbital cavernous venous malformation excision

This is a review of 290 patients who underwent excision of orbital cavernous venous malformations (OCVM) between 1970 and 2021, looking to identify the risk factors for a poor visual outcome following surgery. Intraconal lesions were classified as Group I,...

Clinical presentation, management, and outcomes in posterior segment open globe injuries

This is a retrospective, non-comparative, interventional case study of patients presenting with scleral and corneoscleral wounds covering a five-year period. It reports the clinical presentation, management, and factors affecting the outcomes of posterior segment open globe injuries (OGI) in 2360...

Surgical correction of lacrimal gland prolapse

This is a systematic review of published literature on the management of lacrimal gland prolapse or ptosis. The authors found 16 publications which contained a description of any surgical correction of a prolapsed lacrimal gland, comprising seven case reports, four...

Ophthalmic presentations and outcomes in Erdheim-Chester disease

This is a comprehensive article describing clinical manifestations and pathogenesis of Erdheim-Chester disease (ECD) followed by a literature review of the available treatments. The authors look to compare historical treatment (HT) with vemurafenib, a BRAF inhibitor. ECD is a non-Langerhans...

Differentiating orbital cellulitis from non-specific orbital inflammation

This is a retrospective study looking at whether common laboratory investigations can help differentiate between orbital cellulitis (OC) and non-specific orbital inflammation (NSOI). NSOI is a diagnosis of exclusion following negative investigations for systemic diseases such as IgG4-related disease, granulomatosis...

Telemedicine for postoperative reviews

This is a detailed study looking at the use of telemedicine in the context of a postoperative review following oculoplastic and orbital surgery. The authors combined a video consultation (telephone if there were technical issues) with a ‘pre-visit tool’ that...

Normative dimensions of the lacrimal gland

This article looks at the normative dimensions of the lacrimal gland in the axial and coronal plane on fat-suppressed T1 weighted contrast-enhanced magnetic resonance imaging (MRI). Previous data on this subject has come from computed tomography (CT). MRI is known...

Evisceration in India: demographic and clinical trends from a large multicentre cohort study

In this multicentre cohort study, the authors investigated a total of 2071 patients who underwent evisceration with primary implant placement over a six-year period at four tertiary eyecare centres in India. Out of 1,345,480 new ophthalmic presentations during the study...

Intravenous ketorolac during DCR

This study compares pain scores postoperatively between patients that received intravenous ketorolac (IVK) pre, intra or immediately postoperatively and a control group that did not receive it. The authors state that the patients were randomised, however it is not described...

Hering’s response in ptosis surgery

his is a prospective study of the Hering’s response in patients undergoing Muller’s muscle-conjunctival resection (MMCR) ptosis surgery, with a particular reference to the accuracy of preoperative phenylephrine testing. Patients with unilateral ptosis were assessed clinically preoperatively, in the immediate...

Pain control during orbital implant surgery

This is a study based on existing evidence that pre-emptive pain control has advantages over traditional post-surgical analgesia. The authors compared pain scores in three groups of randomly assigned and masked patients all undergoing orbital implant surgery under general anaesthesia...