You searched for "regenerative"
RTP801 as a neuroprotective and axon regenerative treatment
1 April 2016
| Wai Siene Ng
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EYE - Neuro-ophthalmology
This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...
Biomaterials and Regenerative Medicines in Ophthalmology (Second Edition)
1 December 2017
| Amtul Mussawar Sami
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EYE - Orbit
With advancement in science and technology in the last decade, the role of biomaterials and regenerative medicines has become increasingly important in the management of various ocular disorders. This book highlights the role of biomaterials in the restoration of vision...
Nano-ophthalmology paves a new path in the future of eyecare
1 December 2022
| Stylianos Mastronikolis, Jayasis Bandyopadhyay
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EYE - General
Introduction The treatments of ocular conditions in the field of ophthalmology varies from topical to surgical procedures. The field of nanotechnology is one of the fast-growing fields of medicine, which plays an important role in turning the impossibilities of the...
OCT in peripheral corneal thinning
This small retrospective study used high resolution optical coherence tomography (OCT) Heidelberg Spectralis to identify features which could determine the underlying aetiology of peripheral corneal thinning. Ten patients were included; five with diagnoses of degenerative peripheral thinning; Terrien’s marginal degeneration...
Modification of surgery to reduce consecutive ET
Surgical treatment for recurrent exotropia (ET) predominantly depends on the primary surgery. Modification of surgical dose may be required in secondary procedures. The aim of this study was to compare surgical outcomes of modified and conventional secondary surgery using lateral...
DVD angle measurements
Surgical treatment for recurrent exotropia (ET) predominantly depends on the primary surgery. Modification of surgical dose may be required in secondary procedures. The aim of this study was to compare surgical outcomes of modified and conventional secondary surgery using lateral...Stem cell therapy for Parkinson’s disease: researching for an effective cure
1 December 2015
| Romina Vuono
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EYE - Neuro-ophthalmology
Neurodegenerative diseases are characterised by the chronic and progressive loss of neurons, which in turn results in loss of cognitive and physical functions. The World Health Organization has estimated that the disability-adjusted life years lost from neurological disease was about...
Climatic droplet keratopathy
1 December 2015
| Bheemanagouda Patil
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EYE - Cornea, EYE - General
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UV-B, ascorbate, environment, human, keratopathy
Climatic droplet keratopathy (CDK) is an acquired and potentially handicapping corneal degenerative disease that is highly prevalent in certain rural communities around the world. It predominantly affects males in their 40’s and is known by many other names such as...
Corneal molecular and cellular biology for refractive surgeon
This is an interesting literature review that looks into the recent advances concerning the corneal molecular and cellular processes that are involved in the wound healing response after excimer laser surface ablation and LASIK surgery. It talks about the complex...Patients blinded by stem cells! How safe are they really?
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Patients blinded by stem cells! How safe are they really? Ever since the successful results following...Genetic profiling for personalised healthcare solutions in AMD – an update
1 August 2015
| Rod McNeil
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EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...
My top five: Innovative approaches to dry AMD
2 February 2024
| Nikhil Sharma
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EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is one of the leading causes of irreversible blindness in the developing world with its prevalence rising alongside age. In societies characterised by ageing populations, it is imperative we explore more effective treatment to alleviate the...
