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Intravitreal aflibercept for diabetic macular oedema
1 December 2015
| Brian Ang
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EYE - Vitreo-Retinal
The VISTA and VIVID randomised phase 3 trial were designed to compare the efficacy and safety of intravitreal aflibercept injections versus laser photocoagulation for diabetic macular oedema (DMO). A total of 872 patients with centrally involving DMO were recruited, and...
Diagnosis of ocular tuberculosis
1 August 2018
| Nikolaos D Georgakarakos
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EYE - Vitreo-Retinal
This review article provides an update on the methods diagnosing ocular tuberculosis (TB), the difficulties in making the diagnosis and makes recommendations to a more accurate diagnosis by combining the available diagnostic tests. Today ocular TB remains a presumptive clinical...
Tacrolimus for endothelial rejection
This double-blinded randomised controlled trial tested the use of adjuvant topical Tacrolimus drops in cases of acute endothelial rejection in penetrating keratoplasty (PK). Patients with typical signs of endothelial rejection were randomised to receive either steroid therapy with topical Tacrolimus...Transconjunctival eyelid weight insertion
This is a description of a new surgical technique to insert upper lid weights via a posterior, transconjunctival route. Following local anaesthetic, the upper lid was everted over a Desmarres retractor with a silk traction suture. A 5mm high central...COVID-19 and the eye: a review of ocular involvement and protective strategies
1 June 2020
| Sohaib Rufai
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EYE - General
A lot of attention has been placed on the use of face coverings to limit COVID-19 transmission, but there has been less focus on ocular involvement and ocular protection strategies. The author reviews the literature and discusses possible solutions. The...
Intravitreal dexamethasone in diabetic macular oedema (DMO) - enhancing the response to anti-VEGF in non- or poor responders
3 February 2023
| Sofia Rokerya
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EYE - Vitreo-Retinal
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Aflibercept, Anti-VEGF, Dexamethasone implant, Diabetic macular oedema, Persistent, Ranibizumab, Resistant
This study aimed to describe the outcomes of a switch back from DEXi (dexamethasone implant) to anti-VEGF therapy in eyes that were treated temporarily with DEXi after an initial poor response to anti VEGF. Twenty-three eyes of 17 patients were...
Endothelial cell loss using different graft injectors in DMEK
This study aimed to investigate endothelial cell loss between two injector systems in descemet membrane endothelial keratoplasty (DMEK) grafts; a glass injector – modified Jones tube and a plastic injector – closed system IOL injector, the Viscoject 2.2 system. DMEK...What's trending Feb/Mar 2019
1 February 2019
| Stephanie Chiu
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EYE - Cataract, EYE - Refractive, EYE - Cornea, EYE - Glaucoma, EYE - General
A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #smartcaptionglasses #Epson #livetheatre #deaf Here is some good news for the New Year. Epson, a Japanese technology firm, has developed...
Endophthalmitis after intravitreal injections in France
1 June 2015
| Efrosini Papagiannuli
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EYE - Vitreo-Retinal
In this nationwide, retrospective, multicentre case series, the authors looked at the incidence and characteristics of endophthalmitis after intravitreal injections of anti-VEGFs and steroids, given for a variety of posterior segment conditions (macular oedema secondary to diabetes or retinal vein...
The management of chronic uveitis
1 October 2015
| Erika Marie Damato, Deva Situnayake
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EYE - Vitreo-Retinal
A 40-year-old company executive is referred from another unit with recurrent anterior and posterior uveitis for 12 months and the inflammatory markers are raised. Review of systems This is a case of chronic uveitis which needs a thorough workup and...
Eye disorders occurring in congenital CMV
The aim of this study was to examine the relationship between congenital cytomegalovirus (CMV) infection and ophthalmological disorders that occur in children and record the frequency and type of eye disorders that occur from the infection. Of 449 potential studies,...Friendly felines and a spot diagnosis
1 June 2014
| Jonathan Park
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EYE - Vitreo-Retinal
A nine-year-old girl presented to me in eye casualty with a three-week history of blurred vision in her left eye. Otherwise she was apparently well, with no past ophthalmic, medical, drug or relevant family history. Visual acuity was 6/4 right...