This case report describes a novel technique where one quarter of Descemet’s membrane (DM) was transplanted during a quarter-descemet membrane endothelial keratoplasty (DMEK) procedure. DMEK graft was prepared from a 58-year-old corneo-scleral donor after one week in culture. Peripheral DM...
Innovations in managing irregular corneas were shared and discussed at the 2018 Congress of the European Society of Cataract and Refractive Surgeons (ESCRS), and we were really pleased to speak to one of the key experts in this area, Farhad...
This study evaluated the long-term outcomes of laser-assisted subepithelial keratomileusis (LASEK) with intraoperative use of mitomycin C (MMC) performed on thin corneas for the correction of myopia. MMC modulates the corneal wound healing response in surface healing, thus reducing the...
This study aimed to establish a database of normative measurements of corneal typography in children aged 5-15 years with the Orbscan IIz corneal topography system. They assessed 100 eyes of 100 children. The mean SimK astigmatism was 0.69±0.35D. The maximum...
An animal study was carried out on 36 rabbits, whose corneas were inoculated with either Acanthamoeba castellanii alone, Pseudomonas aeruginosa alone or both pathogens together after a period of short (two hours) or long (six hours) co-incubation. The clinical severity...
This animal study looked at corneal lenticule allograft transplantation in rabbits. Seven rabbits underwent small incision lenticule extraction (SMILE) procedures, where their stromal lenticules were extracted and transplanted fresh into pre-prepared corneal stromal pockets of seven recipient eyes. Animals were...
This was a retrospective non-comparative, interventional case series of 50 eyes in 50 patients with symptomatic PBK who underwent CXL (epithelium-off). Central corneal thickness (CCT), pain score, best corrected visual acuity (BCVA), and corneal transparency were recorded at baseline; at...
This retrospective study examined outcomes of the largest reported series of eyes, which underwent Descemetorhexis without endothelial keratoplasty (DWEK) for Fuch’s endothelial dystrophy with mean 10 months of follow-up. Seventeen eyes were included in analysis; with 82.4% achieving corneal clearance...
Transcriptomics is defined as the analysis of the complete set of RNA transcripts present in a cell under different circumstances, quiescent versus challenge, by microarray analysis. Comparison of transcriptomes identifies genes that are differentially expressed in different cell populations under...
The cornea is an immune privileged site and as such corneal transplants are very successful. However, in situations where this privilege is lost the failure rises substantially. To combat rejection inhibition of the immune responses depends on steroids and other...
This case series described the use of a novel technique in the treatment of descemetocele. Three patients developed descemetoceles following infective keratitis with impending risk of corneal perforation. Platelet rich fibrin (PRF) membrane was prepared using 8ml of fresh venous...
MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...