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Lacrimal gland carcinoma outcomes

This is retrospective review of outcomes of lacrimal gland epithelial tumours treated between 1972 and 2014 at Moorfields Eye Hospital. Seventy-nine patients were reported, comprising 53 adenoid cystic carcinomas, 15 primary adenocarcinomas and 11 carcinomas ex-pleomorphic adenoma. The authors compare...

Ovarian hormones drive onset of Sjogren’s disease in mice

Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...

What's trending Feb/Mar 2018

We are officially in 2018. New year, new you. The clock starts to turn to midnight and suddenly the excess and gluttony of the Christmas festive period comes to mind. “This year will be better”, we say to ourselves. The...

The results of the last survey Aug 2019

Thank you once again for participating in the survey. Some fascinating results once again. Almost one in five of us do not cancel cataract surgery on the day if the blood pressure (BP) is high, which I am surprised about....

Unconscious bias (part 2)

Does unconscious bias exist, and does training help to reduce discriminatory behaviour? Clare Inkster questions her role as a trainer. I read Gwyn Williams’ Learning Curve article on this topic a few months ago with interest, and as someone who...

Avoiding pre-placed recti sutures in enucleation

This is a retrospective review of 40 patients who underwent enucleation using a non-conventional technique in which the recti muscles were detached from the sclera without pre-placing any sutures to secure the cut muscle ends. The surgery was only performed...

Ocular adnexal mantle cell lymphoma

In this study the authors compare primary ocular adnexal (OA) mantle cell lymphoma (MCL) with initially systemic MCL occurring over a 30-year period. MCL is a rare form of lymphoma accounting for 5-11% of OA lymphomas and therefore knowledge of...

Can coenzyme Q10 have a protective role in ethambutol-induced retinal ganglion cell toxicity

Tuberculosis (TB) is one of the most prevalent infectious diseases, especially in developing or low- income countries. Ethambutol is a widely used drug to treat TB. Ethambutol can cause visual disturbance including ethambutol toxic optic neuropathy (ETON). ETON is one...

Ocular blood flow changes in Behcet disease

This study evaluates ocular blood flow changes in both ocular Behcets disease (BD) and non-ocular BD (with or without thrombotic disease) and compares these findings with a healthy control group. A total of 90 eyes with BD were evaluated with...

Meta-analysis of treating meibomian gland dysfunction (MGD) with topical / oral azithromycin

This study pooled the clinical outcomes of 18 high-quality studies managing MGD with azithromycin. Symptom score was the primary and clinical signs were the secondary outcome measures. Overall effectiveness of topical azithromycin (TA) and oral azithromycin (OA) was measured by...

Sebaceous gland carcinoma

This is a review of 241 patients diagnosed with periocular sebaceous gland carcinoma which investigates whether age at presentation influences either the clinical presentation or the outcomes of treatment. Twelve percent of patients were classified as young (<40 years old),...

Tear production levels and dry eye disease

Dry eye disease (DED) is multifactorial, caused by an alteration in the quality or quantity of tear film’s three layers. Several tests are available for diagnosis. The aim of this study was to determine if the Schirmer test (ST) could...