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Bromfenac versus betamethasone in diabetic macular oedema
This is a randomised, prospective, single-centre trial in patients diagnosed with diabetic macular oedema (DMO) with central subfield thickness (CST) of 250-500µm, who refused anti-VEGF treatment. Nineteen eyes of 19 patients were randomised to bromfenac (BF) or betamethasone (BM) drops,...
Ophthalmic presentations and outcomes in Erdheim-Chester disease
This is a comprehensive article describing clinical manifestations and pathogenesis of Erdheim-Chester disease (ECD) followed by a literature review of the available treatments. The authors look to compare historical treatment (HT) with vemurafenib, a BRAF inhibitor. ECD is a non-Langerhans...
Prevalence and related factors for strabismus and amblyopia in Africa
The aim of this study was to overview the literature in relation to strabismus and amblyopia and associated risk factors in Africa. The review included 24 papers; eight for strabismus and 21 for amblyopia. Sample sizes ranged from 352 to...
Myopia in Han Chinese
The authors present a case-control study of 361 patients with high myopia (mean spherical equivalent of -6.0DS or lower, and axial length greater than or equal to 26mm) and 749 healthy controls (mean spherical equivalent -1.0 to +1.0DS). They tested...
Choice of diclofenac or corticosteroids for strabismus surgery
This systematic review was undertaken to analyse the available data on various corticosteroids and diclofenac to determine the most effective postoperative anti-inflammatory agent for patients with strabismus. Twenty-five studies were identified from 1997–2021 and a total of eight met the...
Progression of macular atrophy in Stargardt disease
The authors present a study of a cohort of patients with genetically proven ABCA4 gene mutation related Stargardt disease. They aimed to quantify the effect of lesion location and topography on disease progression using fundus autofluorescence imaging. One hundred and...
Comparison between findings in ‘active’ or ‘healed’ giant cell arteritis
Giant cell arteritis (GCA) is the most common systemic vasculitis in older people and can cause devastating sight loss if untreated. Temporal artery biopsy is often relied upon for diagnosis by ophthalmologists, with a positive biopsy result indicating whether the...
Clinical predictors of proliferative sickle cell retinopathy
Sickle Cell Disease (SCD) is an inherited disorder resulting in production of Haemoglobin S (HbS), which aggregates in conditions of hypoxia, acidosis or hyperosmolarity. This leads to vascular stasis, thrombosis and ischaemia. The authors present a cross-sectional study (45 consecutive...
Transsynaptic retrograde degeneration linked to homonymous visual field loss after stroke
centre, of individuals identified with homonymous visual field loss post ischaemic stroke. Exclusion criteria were bilateral ischaemia, anterior / pregeniculate visual pathway affected and other pathology with the potential to effect visual fields. The following were extracted from the medical...
Intermittent manual compression for CCF
Carotid cavernous fistulae (CCF) can be classified as high and low-flow or as having direct and indirect communication. Most commonly, management of high-flow CCF is with endovascular embolisation. The authors look at an alternative treatment for CCF in indirect low-flow...
Posterior circulation stroke associated demographics, risk factors and aetiology
The authors present a retrospective case notes review of patients diagnosed with homonymous hemianopia following a radiologically confirmed stroke. A total of 85 patients were identified by searching an electronic medical records system over an 11-year period. Data were extracted...
