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Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

Broadening of treatment options for potentially blinding retinal conditions

Rod McNeil provides an update on a promising bispecific antibody recently approved for treatment of neovascular age-related macular degeneration (nAMD) and diabetic macular oedema (DMO) and considers emerging developments in biosimilars to established anti-vascular endothelial growth factor (anti-VEGF) therapies, including...

A life outside ophthalmology

Lloyd Paul Aiello. It was an absolute privilege to speak to Lloyd Paul Aiello, Professor of Ophthalmology, Harvard Medical School, and Vice President of Ophthalmology and Director, Beetham Eye Institute, Joslin Diabetes Center, USA. Prof Aiello is a third-generation ophthalmologist,...

Neuro-ophthalmology: the extended role of an orthoptist

Neuro-ophthalmology has always been a speciality of interest during my studies and now in my career. In 2018, I started a Band 7 post which gave me an extended role in neuro-ophthalmology and the responsibility of developing an orthoptic led...

Eyes on Tomorrow podcast: “Desert Island Discs for ophthalmologists”

What happens when an ophthalmologist and optometrist get chatting in a pub, over a couple of pints of Guinness, about how they could create something educational and entertaining for ophthalmologists and optometrists? The answer is the Eyes on Tomorrow podcast....

Santorini sunlight!

In the heart of London, Hollywood icon Keanu Reeves attended his inspiring book launch event held at the Royal Festival Hall, later followed by a book signing at Waterstones in Piccadilly, London. Ticket holders included ladies from the Literacy Ladies...

Conference Preview: UKISCRS, UKISOP and YOP 2025

London’s calling, and we will be rejoining the United Kingdom & Ireland Society of Cataract & Refractive Surgeons (UKISCRS), the Young Ophthalmologists Programme (YOP), and United Kingdom & Ireland Society of Ophthalmic Practitioners (UKISOP) between 12–14 November. The former will...

Acetylcholine receptor antibodies in the diagnosis of ocular myasthenia gravis at the Manchester Royal Eye Hospital

Myasthenia gravis (MG) is the commonest autoimmune condition to affect the neuromuscular junction. In the UK, its prevalence is 15 per 10,000 [1,2] and recent studies have shown that rates are steadily increasing [3,4]. Aims of this audit The aim...

Learning from litigation: ocular drug toxicity

Being the subject of litigation is stressful and upsetting. Having to look back over your previous decisions and justify the care you delivered in good faith can be difficult. Sadly, we all live with the sword of Damocles above us...

Aqueous misdirection: a case series of unexpected surgical complications

Aqueous misdirection (AM), also known as malignant glaucoma, is a form of secondary glaucoma that typically presents with shallowing of the anterior chamber (AC), raised intraocular pressure (IOP), and reduced visual acuity (VA) in the presence of patent peripheral iridotomies...

IN FOCUS - The achievements and lasting effects of VISION 2020

Blindness is a major public health problem globally. The first estimate of global blindness by the World Health Organization (WHO) in 1972 provided a figure of 10 to 15 million, which was considered an underestimate [1]. In 1999, an extraordinary...

The Diabetic Eye Screening Programme in Tanzania - The VISION 2020 LINK between Dodoma and Belfast

Rahila Bashir, Senior Remote Ophthalmic Research Image Grader, talks to Frank Sandi, Ophthalmologist at the Benjamin Mkapa Hospital (BMH), University of Dodoma in Tanzania and to Tunde Peto at Queen’s University Belfast (QUB) and Belfast Health and Social Care Trust...