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Non-organic visual loss

Patients can present to eye departments with various signs and symptoms (mostly symptoms) with no obvious organic cause. These patients can be labelled with any of a wide range of diagnoses such as functional visual loss, functional overlay, psychosomatic reaction...

Macular imagery: observing the visual sensations pre- and post-Jetrea injections

A 63-year-old woman, a professional painter, was diagnosed with vitreomacular traction (VMT) in 2017. She had a history of metamorphopsia, drop in visual acuity (VA) in the left eye (6/6 in the RE; 6/18 in the LE), foveal vitreomacular traction...

I am interested in making my ophthalmology practice sustainable, but where do I start?

I have yet to meet an ophthalmologist who does not care about a sustainable future for our planet, but the challenge lies in knowing where and how to start. Quite often, as individuals, we see ourselves less empowered when it...

How many injections in nAMD: ranibizumab vs. aflibercept

Intravitreal anti-VEGF injections make up a large proportion of the workload in ophthalmology clinics. Since the introduction of aflibercept with eight weekly injections there has been an option to use a treatment which may require less treatment, with potential cost...

Surgery for superior oblique palsy with superior rectus contracture

With limited information in the literature regarding simultaneous surgery in cases with superior rectus (SR) contracture in superior oblique (SO) palsy, the authors aimed to evaluate the efficacy of combined SR/IO surgery. This was a retrospective study of 15 cases...

From Dye to Digital: Why OCTA is replacing invasive imaging in retinal care

For decades, retinal imaging has relied on invasive dye based techniques to visualise the eye’s vasculature. However, Optical Coherence Tomography Angiography (OCTA) is fast becoming the preferred modality, replacing fluorescein and ICG angiography in many clinical settings. As highlighted by...

My top five Apps for UK-based general ophthalmologists

The way we interact in society is changing as more of us are becoming ‘digital natives’: individuals who are in close contact to the internet and expect to integrate smart devices with our daily lives. This was stereotypically a term...

My Top Five: Apps for UK-based general ophthalmologists

The way we interact in society is changing as more of us are becoming ‘digital natives’: individuals who are in close contact to the internet and expect to integrate smart devices with our daily lives. This was stereotypically a term...

RaScaL Study

The RaScaL study was a six month, single-centre, controlled, prospective phase I/II study in which subjects with diabetic macular oedema (DME) and associated peripheral nonperfusion on ultrawide-field fluorescein angiography (UWFA) were randomised to: (1) study arm: ranibizumab (0.5 mg) injection...

Resveratrol protects against steroid induced intraocular pressure

Topical and systemic steroid delivery is a very effective treatment for many ocular conditions but is compromised by raised intraocular pressure which in turn leads to death of retinal ganglion cells and irreversible blindness. This is an important consideration with...

Somatostatin protects retinal pericytes

Diabetic retinopathy (DR) is a complication of diabetes, caused by high blood sugar levels damaging the retinal microvasculature. Mechanisms, such as oxidative stress and deposition of advanced glycation end products, leads to glial cell activation and neuronal apoptosis. Pericytes, contractile...

Cataract surgery and circadian photoentrainment

The study authors sought to investigate the possible effects of circadian photoentrainment following cataract. This was a randomised clinical trial, where 76 eyes of 76 patients (with bilateral cataract) were randomised to blue-blocking or neutral intraocular lenses (IOLs). Outcome measures...