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OCT choroidal signs for congenital retinal pigment epithelium hypertrophy

Congenital hypertrophy of the retinal pigment epithelium (CHRPE) on ocular coherence tomography (OCT) has the characteristic sign of RPE thickening and hyper reflectivity. However, the underlying choroid characteristics remain under researched. This retrospective study utilised data from an ophthalmic oncology...

Assessment of retinal capillary VD and FAZ area in CSC using OCTA

The authors aim to report a cross-sectional, case controlled study, the purpose of which was to access the retinal capillary vessel density (VD) and foveal avascular zone (FAZ) area in acute and chronic central serous chorioretinopathy (CSC) patients compared to...

Good News from Switzerland: A History of Retinal Reattachment Surgery

In one concise volume the reader learns of the recent rapid evolution in vitreoretinal (VR) surgery. The pioneering innovators were often remarkable personalities and this book helps to bring them to life. Prior to 1929 victims of retinal detachment were...

Changes, with increasing age of children, in optic nerve head parameters and retinal thickness

In this study, the authors aimed to compare stereometric parameters of the optic disc and inner retinal layer thickness (peripapillary retinal nerve fibre layer (pRNFL) and ganglion cell inner plexiform layer (GCIPL)) at two time points in the same children...

Density of cataract and its influence on retinal nerve fibre layer thickness

The aim of this study was to further define and model the influence of cataract on spectral domain optical coherence tomography (SDOCT) image quality and retinal nerve fibre layer (RNFL) thickness measurements. OCT quality is influenced by opacities in the...

Comparing retinal thickness in Parkinson’s disease, essential tremor and healthy controls

This study aimed to compare retinal findings in chronic essential tremor (ET), early Parkinson’s disease (PD) and healthy controls. Those recruited with ET had to have received a diagnosis a minimum of three years previous and those with PD had...

The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy

The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...

Significant associations to presence of significant retinal haemorrhages in suspected child abuse

The authors aimed to extract statistically significant associations between non-ocular clinical and diagnostic imaging findings and the presence of significant retinal haemorrhages, and then develop an evidence-based screening algorithm to determine when to consult an ophthalmologist in suspected child abuse...

A rare case of post-traumatic central retinal artery occlusion

Central retinal artery occlusion is rarely associated with traumatic optic neuropathy, this case report details of one such case. The reported case is of a ten-year-old boy presenting after a fall from height with loss of vision in one eye....

Ginko bilboa extract affects hypoxic retinal pigment epithelial cells

Wet age-related macular degeneration (AMD) is characterised by choroidal neovascular membrane (CNVM) formation. It is thought that localised hypoxia within the retina results in overexpression of growth factors such as vascular endothelial growth factor (VEGF), which induces CNVM formation. VEGF...