You searched for "inflammation"
Glaucoma medications and ocular surface disease
3 August 2023
| Su Young
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EYE - Glaucoma
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Drug allergy, OSD, drug toxicity, drug-induced cicatricial keratitis, dry eye, glaucoma medications, ocular surface disease
This literature review examined ocular surface disease (OSD) associated with glaucoma medication. The authors examined the prevalence of features and management guidelines glaucoma medication associated OSD. Fifty-eight articles published within the past five years are included in this review and...
Review of extraocular muscle biopsies and utility of biopsy in extraocular muscle enlargement
This is a retrospective case series study from Melbourne, Australia, of 93 patients with extraocular muscle (EOM) enlargement who underwent an EOM biopsy between March 1992 and January 2017. Statistical analysis was performed to compare the data between patients with...Quiz Oct/Nov 2022
3 October 2022
| Aaron Carlisle, Joseph Houghton
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EYE - General
History An Afro-Caribbean woman, aged 30, with “scleral tattooing” for cosmetic reasons (subconjunctival dye injection), presented with bilateral upper and lower eyelid oedema for one week, and she also had restricted eye movement and blurry vision in her right eye....
New genomic test saves Moorfields patient’s sight
Moorfields patient Ellie Irwin’s stubborn and debilitating eye inflammation was successfully treated as a result of a new metagenomic service identifying the cause of this as a rare infection. In 2019, Ellie first got symptoms of uveitis, a condition characterised...
Case series of posterior scleritis
This report aimed to facilitate the correct diagnosis of posterior scleritis, a condition which is usually overlooked or misdiagnosed. Electronic health records of 31 patients with posterior scleritis were analysed and compared to a group with isolated anterior scleritis of...
Interesting causes and consequences of orbital inflammations
Three articles discuss various causes and consequences or orbital cellulitis. The first highlights the possibility of orbital cellulitis causing cavernous sinus thrombosis and in the case presented progression to internal carotid artery aneurysm. The authors highlight the importance of considering...Immunoglobulin G4-related ophthalmic disease – what is it? (Part 2)
3 April 2023
| Li Yen Goh
Part 2: Clinical presentation and treatment (see part 1 here) Introduction IgG4-related disease (IgG4-RD) is understood to have a vast clinicopathological spectrum; nearly every organ has had reported involvement. Similarly, IgG4-related ophthalmic disease (IgG4-ROD) is known to affect nearly every...
Does a gut-eye axis exist?
1 October 2019
| Simerdip Kaur
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EYE - General
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Does a gut-eye axis exist? Over a decade ago, the Human Microbiome Project was launched by...
Neurotrophic keratitis
The authors present an overview of the aetiology, diagnosis, current and future management options of neurotrophic keratitis. This is a degenerative corneal disease that occurs following the compromise of trigeminal innervation, leading to hypoesthesia and / or anaesthesia. The aetiology...Typical and atypical optic neuritis – diagnosis and initial management
1 June 2016
| Srilakshmi Sharma, M Isabel Leite
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EYE - Neuro-ophthalmology
Optic neuritis is a relatively common presentation to ophthalmologists in the acute setting. The vast majority are cases of ‘typical’ optic neuritis (ON) but a smaller group of conditions, so-called, ‘atypical’ optic neuritides require a different work-up and management strategy....
Topical cyclosporine A 0.05% for recurrent anterior uveitis
1 August 2016
| Jonathan Chan
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EYE - Vitreo-Retinal
This is a retrospective case-crossover study conducted by reviewing medical charts of patients treated for recurrent anterior uveitis between 2002 and 2011 at the Kellogg Eye Centre by one cornea specialist. The demographics, episodes of anterior uveitis, severity of episodes...
Ovarian hormones drive onset of Sjogren’s disease in mice
1 December 2014
| Graham Wallace
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EYE - Cornea, EYE - General
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Sjögren’s Syndrome, lacrimal glands, sex hormones, cytokines, anti-Ro/SSA, anti-La/SSB, NOD.B10.H2b
Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...
