You searched for "choroidal"
Risk factors and prognosis of paediatric open globe injuries
1 October 2021
| Sofia Rokerya
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EYE - Vitreo-Retinal
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Choroidal damage, Endophthalmitis, No light perception, Pediatric open globe injuries, Vitreoretinal surgery
This retrospective, comparative, interventional case-control study was aimed to investigate possible risk factors and prognosis of initial no light perception (NLP) in paediatric open globe injuries (POGI). A total of 851 cases were reviewed, including 837 unilateral cases and 14...
Comparison of retinal pigment epithelium-choroid graft surgery and anti-VEGF therapy in patients with wet AMD
1 December 2015
| Sofia Rokerya
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EYE - Vitreo-Retinal
This was a randomised intervention study in wet AMD patients to investigate benefits of free RPE-choroid graft transplantation surgery versus (continuation of) anti-VEGF treatment. Twenty patients who met the inclusion criteria were subdivided into three subgroups, i.e. RPE tears involving...
25 years of OCT
David Huang first described optical coherence tomography (OCT) in 1991, in his seminal paper on the subject in Science. This method developed the work of others on ophthalmic interferometry, which essentially showed that measuring reflected light could be used to...The embryology of the eye
1 December 2015
| Jacob Cook
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EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Orbit, EYE - Oncology, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Nobody claims to like embryology. At least nobody I know. It has been a neglected part of the curriculum since time immemorial and a vicious cycle occurs in which those with an incomplete understanding fail to appreciate the inherent beauty...
Choroid and retinal changes post COVID-19
The authors aimed to evaluate choroid and inner neural layers in people previously recovered from Covid-19 compared to healthy controls using optical coherence tomography (OCT) over a six-month period. They recruited 96 people: 56 with Covid-19 at least three months...The approach to angle-closure glaucoma
1 October 2016
| Kaivon Pakzad-Vaezi
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EYE - Glaucoma
Further to my last article in Eye News (print issue) describing the diagnostic approaches to various clinical scenarios in glaucoma, the approach to angle-closure glaucoma (ACG), a situation terrifying for patient and registrar alike, will be discussed. Please refer to...
Melanocytoma of the optic disc
1 June 2015
| Lucia Derriman, Sumith Perera
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EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Melanocytoma is a heavily pigmented lesion, composed of melanocytes and is a variant of melanocytic naevus. It classically occurs at the optic disc and is usually benign, static and asymptomatic. However, it can occasionally grow and invade the retina or...
Moorfields Education: Hot topics in comprehensive ophthalmology
7 February 2025
Hot topics in comprehensive ophthalmology is a course for people who work in the field suitable for comprehensive/general ophthalmologists, urgent care and primary care, optometrists and nurse practitioners. This is an update on common themes which appear in the comprehensive...
Nicotine accelerates diabetes induced retinal changes
1 June 2015
| Khadijah Basheer
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EYE - Vitreo-Retinal
This study investigated the influence of nicotine in an experimentally induced diabetic rat model. They used non-invasive high-resolution spectral domain optical coherence tomography (SD-OCT) imaging to provide quantitative information on the temporal alterations of retinal structures at the micrometer resolution...
ABCA1 mediates lipid efflux in the retina
1 June 2018
| Graham Wallace
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EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population. There are two forms of AMD, dry and wet, the latter so named because of the presence of choroidal neovascularisation. Both forms lead to retinal pigment...
A mouse model for uveal melanoma
Uveal melanoma (UM) is the most common malignant tumour arising within the eye and is a severe threat for both sight and life, due to a high risk of metastasis. There are no animal models of UM, but the Tg(Grm1)...
Complement factor B polymorphism and the phenotype of early age-related macular degeneration
1 August 2014
| Huw Edward Oliphant
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EYE - Vitreo-Retinal
The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...
