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1865 results found

HtrA1 enhances cell senescence

A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...

AAO cancels meeting for first time since 1945

The AAO has announced that its 2020 meeting will now be virtual only.

Manchester medical retina team to host free macula course

The Manchester Macula Course will be held virtually on Wednesday 15 September and Wednesday 29 September.

Ranibizumab for the treatment of age-related macular degeneration

This multicentre randomised prospective open label study compared 0.5 versus 2mg of ranibizumab in patients with submacular retinal pigment epithelial (RPE) detachment due to age-related macular degeneration. Four treatment regimens were used for the two strengths either monthly for 12...

Fixation target position for increased limbus measurement accuracy with AS-OCT

The authors intended to determine the optimal gaze fixation points for lateral rectus and medial rectus muscle insertions using anterior segment - optical coherence tomography (AS-OCT) compared with intraoperative measurements. They recorded 46 lateral and 36 medial rectus muscles from...

Use of the Mendonca strabismus forceps in locating and measuring muscle insertions

The authors aimed to compare the reliability of the Mendonca strabismus forceps vs intraoperative calliper measurements for determining the distance from the limbus to the insertion of the extraocular muscles in patients undergoing strabismus surgery. This was a prospective observation...

Transfected RPE cells inhibit AMD in rats

Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. Wet AMD is characterised by choroidal neovascularisation, new vessels into the retina, leading to leakage and tissue damage. Many proangiogenic factors particularly vascular endothelial growth factor (VEGF)...

Microcatheter in the vertebral artery as a cause of branched retinal artery occlusion?

A 19-year-old male presented to eye casualty with a seven-day history of a ‘blurred patch’ in the left eye. The patient denied any other visual symptoms including flashes or floaters and there had been no change in visual symptoms in...

The bionic eye – behind the headlines

Multiple visual prosthetic projects and other vision regeneration initiatives being tested in preclinical and clinical development worldwide illustrate continuing progress and opportunities in addressing profound blindness from hereditary retinal diseases and other causes (Table 1). Three implantable bionic vision systems...

Retrospective analysis on the outcomes of contact lens-associated keratitis in a tertiary centre

This is a retrospective cohort study of 161 eyes (153 patients) with contact lens-associated keratitis (CLAK) from Moorfields Hospital between 1 July 2021 to 28 February 2022. They were classified into three groups based on the size of the epithelial...

Patients blinded by stem cells! How safe are they really?

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Patients blinded by stem cells! How safe are they really? Ever since the successful results following...

Gene profiling for a family with Duane’s retraction syndrome

The aim of this study was to describe the clinical and genomic features of a family with special types of Duane’s retraction syndrome (DRS). The mother and son had obvious clinical features. The son displayed features of horizontal gaze palsy...