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Neurofibromatosis type 2 – diagnosis, features and MDT approach
NF2 is a genetic condition caused by mutation in a single gene (NF2 gene) on chromosome 22. The NF2 gene provides instructions to produce a protein called merlin, also known as schwannomin. This protein functions as a tumour suppressor, preventing...Four Pillars: Leadership for clinical practice settings
This series explores the four pillars of advanced clinical practice and here, Regina Tavengwa explores the pillar of leadership and management. I have been in my current role as a matron for eight years, with a background of practicing as...Diabetes and diabetic retinopathy: Changes in understanding of the disease over the last 25 years and how the UK is helping low-income countries tackle the challenges
Diabetes – a historical perspective Diabetes mellitus (DM) is a chronic disease caused by inherited and / or acquired deficiency in production of insulin by the pancreas, or by the ineffectiveness of the insulin produced. Such a deficiency results in...Applying for ophthalmology ST1 in 2026: What’s new?
Competition for ophthalmology ST1 has intensified steadily over recent cycles, rising from ~9:1 (2022) to ~10:1 (2023), ~14:1 (2024) and ~22:1 (2025) [1]. Against this background, applicants benefit from a structured approach: mapping achievements to portfolio domains early, identifying gaps...A missed opportunity
Back in 2000 Sir Liam Donaldson wrote a piece of work commissioned by the then Secretary of State for Health entitled “An Organisation with a Memory”. We are now 18 years on and still some of the recommendations from them...Intracameral antibiotics in cataract surgery: current evidence base
Following on from our recent online survey*, the authors examine the use of intracameral cefuroxime as the standard of care in cataract surgery. Cataract extraction with intraocular lens implantation is one of the most frequently performed surgical procedures in the...Designing ophthalmology services - Part 1: How do we address the queues in a clinic?
This first of a three-part series shows how systems engineering can be used to correctly diagnose and address the causes of delays in a clinic. The second article, which will be featured in the April/May 2020 issue, describes how to...Glaucoma UK announces winners of the 2025 ‘Excellence in Glaucoma Care Award’
Glaucoma UK is delighted to announce the winners of this year's Excellence in Glaucoma Care Awards – Patrick (Paddy) Gunn from Manchester and Alex Gage Family Optometrists in Sheffield. This annual award celebrates individuals or teams who have made remarkable...Dec/Jan Quiz 2014
History A 25-year-old West African male presents with oral candidiasis, generalised lymphadenopathy and a red nodule in the left upper eyelid. This is biopsied. See histology images. Figure 1. Figure 2. Figure 3. Questions 1. Describe Figure 1 (haematoxylin and...
A standardised strategy for uveitis etiological diagnosis
This was a prospective, non-inferiority, multicentre randomised control trial, which aimed to assess the effectiveness of a standardised approach in the etiological diagnosis of uveitis versus an open strategy, where clinicians could perform any test. The authors developed their standardised...
