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Comparison of treatment regimes for APROP
The authors evaluated the risk factors and treatment outcomes of various treatment options for APROP including intra-vitreal anti-VEGF injections, laser treatment and a combination of both. This was an observational study of all consecutive cases of untreated APROP from 2018-19...
Visual prognosis in Irish Leber’s hereditary optic neuropathy
Leber’s hereditary optic neuropathy (LHON) is an inherited optic neuropathy This paper presents a retrospective review of clinical data from patients with LHON presenting to an Irish tertiary referral ophthalmic hospital. Clinical and genetic characteristics were assessed for useful biomarkers...
Could internuclear ophthalmoplegia aid differential diagnosis in demyelinating conditions?
The authors present a retrospective review of individuals diagnosed with either neuromyelitis optica spectrum disorder (NMOSD) or multiple sclerosis (MS). The aim of the study was to assess the prevalence of internuclear ophthalmoplegia (INO) in both groups over a 10-year...
Treatment of diabetic macular edema in vitrectomised eyes – comparison of intravitreal dexamethasone implant and posterior subtenon triamcinolone injection
This retrospective study was aimed to compare intravitreal dexamethasone implant and posterior subtenon triamcinolone injection (PSTA) in the treatment of diabetic macular edema (DME) in vitrectomised eyes. Sixty-four (48.12%) patients who had received PSTA and 69 (51.88%) patients who had...
Current concepts of the uveitis-glaucoma-hyphaema (UGH) syndrome
The authors discuss pathophysiology, aetiology and current management strategies of UGH syndrome. The clinical features of UGH are different than initial descriptions. UGH today is most often associated with posterior chamber IOLs that are not placed within the capsular bag...
How common are ocular disorders in the first 12-months of life?
The authors present a retrospective case review of all children aged under one year of age diagnosed with an ocular disorder over a 10-year period. The aim of the study was to describe incidence and types of ocular disorder in...
Effectiveness of supramaximal horizontal surgery for third nerve palsy
The purpose of this study was to present the outcomes and progress of third nerve palsy cases after supra-maximal recession / resection. The aim is for an initial overcorrection of 15-25PD at day one. This was a retrospective study of...
Use of telemedicine within adult strabismus management
The aim of this survey was to assess the practice preferences in the management of adult strabismus among the American Association for Pediatric Ophthalmology and Strabismus (AAPOS) committee members. A 27-question multiple-choice questionnaire was sent to 19 ophthalmologists on AAPOS...
Transcriptomic and regulatory gene associations in open angle glaucoma
The authors report a study utilising a publicly available whole exome sequencing dataset of 28 patients with primary open angle glaucoma (POAG) and seven healthy control patients, and a transcriptomic dataset from the trabecular meshwork of four POAG patients and...
Recommendation for wide angle fluorescein angiography to diagnose FEVR in NEDSDV
Neurodevelopmental disorder with spastic diplegia and visual defects (NEDSDV) is a genetic disease described in 2012 associated with variants in the CTNNB1 gene which encodes beta-catenin. Characteristics include strabismus, reduced visual acuity and familial exudative retinopathy (FEVR). In this study,...
