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G-CSF intravitreal injections for NAION: a pilot study

In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...

Reproductive counselling for females with X-linked inherited retinal diseases

The authors report a survey-based study of 118 female patients who were genetically confirmed carriers or obligate carriers of an X-linked inherited retinal disease. The majority (66.9%) of these patients were carriers of choroideremia; other diagnoses included retinitis pigmentosa, X-linked...

Birmingham Optical Achieves UKAS ISO 9001 Certification

Birmingham Optical, a leading UK provider of optical equipment and services, has been awarded the prestigious UKAS ISO 9001 certification, a globally recognised standard for quality management systems (QMS). This milestone reflects the company’s dedication to excellence, consistency, and customer...

OSA regulatory advice baton moves to new expert

The OSA’s regulatory advice service – a key element of membership for many optical businesses – is moving to safe new hands as Ann Blackmore retires after six years at the helm. Ann’s extensive knowledge of the optical landscape, both...

In conversation with Andrena McElvanney (President, MCLOSA)

We spoke to Andrena about MCLOSA's annual meeting this November, key developments in cornea and external eye disease, and plans for the association’s 30th anniversary. Andrena McElvanney (top, second from right) and the OSI council members. The Medical Contact Lens...

A nightmare on Doctor Street: Three

“Everyone at this party isn’t as young, fit and single as they’re making out. Yep, let’s face it, we’re all falling apart piece by piece. Doesn’t matter if you’re single or in a couple: You. Are. Going. To. Die” In...

In vivo confocal microscopy, principles and use in keratitis Part 1: Principles

In 1968 Maurice introduced the concept of high powered specular microscopy, it was in that very year that the first scanning confocal microscope was proposed. Marvin Minsky developed the first confocal microscope in 1955 named the ‘double focusing scanning microscope’....

Chemical injury

You are the on-call ophthalmologist. You receive a call from A&E regarding a 45-year-old man who sustained a chemical injury. He was mixing some cement, when a small amount entered his left eye. He was not wearing any protective goggles....

The Case of Dr Bawa-Garba – Where does the buck stop?

The case of Hadiza Bawa-Garba has left all of us in the UK medical profession with an uncomfortable taste in our mouths. We all know that we work under pressure and we will inevitably make mistakes. We all know that...

Recognising responsibility, breakthrough design

Celebrating achievements in the international optical world, the 30th anniversary of the Silmo d’Or Awards was a spectacular event. Eyewear designers, international media and senior optical executives and VIPs were welcomed to the underground halls of the Carrousel du Louvre...

Dans le Noir

There is a restaurant in London where dinner is served in the dark. Not dim light or occasional infrequent light, but absolute pitch black darkness. Apparently the aim is twofold; to better appreciate the quality of the food as the...

Bosch-Boonstro-Schaaff optic atrophy syndrome (BBSOAS) NR2F1 mutation

An experienced ophthalmologist can make an anatomical diagnosis of childhood visual impairment based upon the surgical sieve, i.e., congenital and acquired. But an ophthalmologist cannot work in isolation to make an aetiological diagnosis – one would require the help of...