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Shifting the paradigm of managing patients in medical retina: how real-world data can help us to improve clinical practice

The ophthalmic subspecialty of ‘medical retina’ has undergone dramatic changes in recent years. With the introduction of ranibizumab (Lucentis, Novartis), a specialty formerly dominated by laser-based therapies has been transformed to become, in large part, pharmacotherapy-based. To date, these pharmacotherapies...

Does bariatric surgery prevent progression of diabetic retinopathy?

The authors report a retrospective observational study of T2DM patients who underwent bariatric surgery between 2009 and 2015. Preoperative and postoperative weight, HbA1c, and annual diabetic retinopathy (DR) screening results were obtained from medical records. Patients with preoperative retinal screening...

Comparison of retinal pigment epithelium-choroid graft surgery and anti-VEGF therapy in patients with wet AMD

This was a randomised intervention study in wet AMD patients to investigate benefits of free RPE-choroid graft transplantation surgery versus (continuation of) anti-VEGF treatment. Twenty patients who met the inclusion criteria were subdivided into three subgroups, i.e. RPE tears involving...

Displacement of submacular haemorrhage – comparative study pneumatic displacement versus subretinal cocktail injection

The authors report a multicentre retrospective interventional case series study comparing the outcome of submacular haemorrhage (SMH) using pneumatic displacement with intravitreal expansile gas versus treatment with pars plana vitrectomy (PPV) versus subretinal injection of tissue plasminogen activator (tPA), anti-vascular...

AI can identify treatment gaps for patients with macular disease, study shows

Using artificial intelligence (AI) in eye clinics could reduce both undertreatment and overtreatment of neovascular or ‘wet’ age-related macular degeneration (AMD). AMD is the leading cause of irreversible vision loss in older people and accounts for around 1 in 10...

Intravitreal Aflibercept (IVT-AFL): treatment of macular oedema secondary to RVO

This paper is a sub-group analysis of the real-world effectiveness, treatment patterns, and safety of IVT-AFL in patients with macular oedema secondary to retinal vein occlusion (RVO) in Italy. One hundred and fifity-two treatment-naïve and 50 pretreated patients were enrolled...

Open globe trauma – visual outcomes after primary vitrectomy

This retrospective study aimed to evaluate the impact of early vitrectomy on visual outcomes in eyes with open globe ocular trauma. One hundred and eighty eyes from a cohort of 166 patients who underwent primary vitrectomy between 2017 and 2023...

What's trending Feb/Mar 2022

A round-up of the eye-related hot topics that have been trending over the last few weeks. British man fitted with 3D printed eye Steve Verze of London has required a prosthetic eye for over 20 years. On 25 November 2021,...

The role of inflammation in the pathophysiology of DMO

Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...

Matt Stringer, RNIB’s Chief Executive Officer commented on the fifth anniversary of start of the Covid-19 pandemic

The UK was woefully ill-prepared for the Covid-19 pandemic, and indeed any type of pandemic, with regards to the rights and needs of blind and partially sighted people. This anniversary still demonstrates that critical lessons need to be learned to...

Matt Stringer, RNIB’s Chief Executive Officer commented on the fifth anniversary of start of the Covid-19 pandemic (1)

“The UK was woefully ill-prepared for the Covid-19 pandemic, and indeed any type of pandemic, with regards to the rights and needs of blind and partially sighted people. This anniversary still demonstrates that critical lessons need to be learned to...

Handbook of Retinal Disease: a case based approach

This book is suitable for all doctors, particularly ophthalmologists, who want to further their knowledge and understanding of retinal pathologies and keep up to date. The case-based format is effective in evoking an interactive approach to differential diagnosis. The tabulation...