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Preventing blindness from diabetes: planning a programme of service development and research across Malawi
In sub-Saharan Africa 19.4 million people have diabetes; this is projected to rise to 28.6 million by 2030 [1]. Sight loss from diabetes devastates the lives of working people, affecting the financial stability of the families and communities who depend...
Scheimpflug images and graft rejection
This study aimed to assess corneal changes using 360-degree Scheimpflug images and pachymetry readings to outline screening parameters, which define graft rejection. Seventeen eyes of 16 patients developed clinically manifest allograft rejection two to 42 months after surgery – those...Survey: Dacryocystorhinostomy International Practice
Dacryocystorhinostomy (DCR) is widely recognised as the gold-standard surgical intervention for managing nasolacrimal duct obstruction, particularly when medical therapy fails to restore adequate lacrimal drainage. Both external and endonasal (endoscopic) DCR approaches have evolved considerably over recent decades, with technological...
Treatment options for septic cavernous sinus thrombosis
Septic cavernous sinus thrombosis is a rare but serious complication of infection of the cavernous sinuses. Potential therapies include antibiotics, corticosteroids and anticoagulation, as well as surgical intervention for source control of the infection. The authors report that there is...
Trabeculectomy ab interno (trabectome)
This retrospective study examines the outcome of trabectome surgery in nine phakic patients with Posner-Schlossman syndrome with uncontrolled IOP >30mmgHg. Cytomegalovirus (CMV) DNA was verified by polymerase chain reaction (PCR) in aqueous humour samples. Patients were treated with oral valganciclover...
Dry eyes after photorefractive keratoplasty
This study examined changes in tear break up time (TBUT), Schirmer test, tear osmolarity and dry eye questionnaire (OSDI) score from prior to photorefractive keratoplasty (PRK), to two months and four months postoperatively. Fifty eyes of 25 patients were examined....
DALK as an early therapeutic option for Acanthamoeba keratitis
Eleven patients with Acanthamoeba keratitis (AK) were treated by early therapeutic deep anterior lamellar keratoplasty (DALK). All surgeries were performed in patients who had no response to standard medical therapy of chlorhexidine gluconate, propamidine isethionate and neomycin sulphate, within 10-15...
Somatostatin protects retinal pericytes
Diabetic retinopathy (DR) is a complication of diabetes, caused by high blood sugar levels damaging the retinal microvasculature. Mechanisms, such as oxidative stress and deposition of advanced glycation end products, leads to glial cell activation and neuronal apoptosis. Pericytes, contractile...
Abducens nerve palsy following surgical correction of craniosynostosis
The authors present two cases of unilateral abducens palsy secondary to a recent trans-sutural distraction osteogenesis (TSuDO) operation for craniosynostosis. The basic principle of the TSuDO procedure is described as dissection and distraction of the prematurely fused sutures. This complication...
Akimba mice, a model of human diabetic retinopathy
Diabetic retinopathy (DR) is a major complication of diabetes and a growing problem as the systemic disease becomes more prevalent. DR develops insidiously from an asymptomatic form through to vascular damage that leads to oedema and breakdown of the blood-retinal...
Pars plana vitrectomy for vitreomacular traction syndrome
This paper presents a meta-analysis and systematic review of the safety and efficacy of vitrectomy for vitreomacular traction (VMT), based on 21 eligible articles from 460 identified. A strength of this study is that it provided pooled analysis across a...
