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Statins inhibit TGFβ2 mediated fibrotic response in astrocytes
Glaucoma is a common condition where increased ocular pressure can lead to death of retinal ganglion cells due to impaired drainage of fluid from the eye. One mechanism involved in glaucoma is remodelling of the extracellular matrix at the lamina...
Outcomes from evisceration with primary implant in 1800 patients
This is a retrospective analysis of 1800 patients who had evisceration with orbital implant between 2013-2019. As the largest published series on this topic, the authors are able to give relatable real-world data on complications following surgery. They use a...FRCOphth oral exam preparation
Elevate your exam preparation with iPrepBuddy, the ultimate tool for busy doctors. Our cutting-edge platform enables real-time interactions with an AI-driven examiner or mock patient, providing scenario-specific feedback to sharpen your skills. Explore our extensive and ever-growing library of cases,...Codifying ‘care’ and ‘cure’ behaviours of artificial intelligence systems: now out in Nature Medicine
A new publication in Nature Medicine discusses 'Building a code of conduct for AI-driven clinical consultations' The diversity of AI applications in medicine is growing at an accelerating rate, with that trend set to continue as technology develops. This diversity...The happiness coefficient: Pete’s hidden curriculum Part 5
Jeremy: Come on, man, shake your booty! Tonight even Paxman’s out, hoovering up lines of crank off Krishnan Guru-Murthy. Tonight’s the big one.Mark: Jeremy, all rational people agree it’s a truth self-evident that it’s impossible to have a good time...Report: UKISCRS 2023
An Eye News exclusive report of The 47th Annual Congress of the United Kingdom & Ireland Society of Cataract & Refractive Surgeons.The role of injection assistant devices in establishing a nurse-led AMD service
The author shares his experience of setting up a nurse-led service to deliver anti-VEGF intravitreal injections and how injection assistant devices supported training. Age-related macular degeneration (AMD) has become a leading cause of irreversible blindness [1]. It is estimated that...In conversation with Christopher Liu OBE
Eye News caught up with Christopher Liu following his recent appointment by Her Majesty Queen Elizabeth II as an Officer of the Most Excellent Order of the British Empire for Services to Ophthalmology. Christopher Liu OBE. Congratulations on your recent...
Climate Change and Eye Disease: Eye Health and Blindness in a Hostile Environment
Climate Change and Eye Disease: Eye Health and Blindness in a Hostile Environment by Scott Fraser offers a thorough examination of how climate change is impacting ocular health. The book explores a variety of eye conditions that are being influenced...
New mouse model of diabetes mellitus
Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...
Fenofibrate and diabetic retinopathy
Fenofibrate is an agonist of peroxisome proliferator-activated receptor-alpha (PPARα) which is used as a lipid-lowering agent. By reducing blood lipid levels, it can decrease retinal hard exudates which is beneficial in diabetic retinopathy (DR). FIELD and ACCORD studies show that...
