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A revolution in modern genetic testing for the clinical management of ocular disease
Recent years have seen a huge increase in our understanding of the genetic factors underlying a wide variety of eye diseases. This has included common conditions such as glaucoma and age-related macular degeneration, as well as those conditions which have...Acanthaemoeba keratitis
In the second of this series I describe a case of Acanthaemoeba keratitis (AK) that was misdiagnosed for a prolonged period which resulted in a devastating outcome. This is one of half a dozen similar medico-legal cases I have dealt...Choroidal melanoma – breaking bad news
Case report A 55-year-old Caucasian female presented to her general practitioner with a three-month history of headaches and worsening blurred vision in the left eye. On further close questioning, she reported no eye pain, intermittent floaters and flashes of light...Revolutionising eyecare: Gloucestershire’s Community Ophthalmic Link delivers nationally significant results
Ophthalmology is the largest outpatient specialty in the NHS, and in Gloucestershire, it is growing at an annual rate of 2.55%, outpacing other specialties. However, rising demand has led to significant waiting lists, often resulting in patients not being seen...Acetylcholine receptor antibodies in the diagnosis of ocular myasthenia gravis at the Manchester Royal Eye Hospital
Myasthenia gravis (MG) is the commonest autoimmune condition to affect the neuromuscular junction. In the UK, its prevalence is 15 per 10,000 [1,2] and recent studies have shown that rates are steadily increasing [3,4]. Aims of this audit The aim...
Comparison of two interferon gamma release assays (IGRA) for tuberculous uveitis
In this prospective cohort study the authors compared QuantiFERON-TB Gold In-Tube and T-SPOT.TB to evaluate their diagnostic accuracy. They enrolled 120 consecutive new uveitis presentations over a two year period in a tertiary centre. The majority were Chinese (61.3%), followed...
The Neuro-Ophthalmology Survival Guide, 3rd Edition
Neuro-ophthalmology, a challenging ophthalmic subspecialty, demands an understanding of neuro-anatomical pathways, nuanced examination and advanced imaging. For ophthalmology trainees, foundation doctors, neurologists and emergency clinicians, it can feel daunting to frequently encounter optic neuritis, visual field defects and cranial nerve...
Interesting causes and consequences of orbital inflammations
Three articles discuss various causes and consequences or orbital cellulitis. The first highlights the possibility of orbital cellulitis causing cavernous sinus thrombosis and in the case presented progression to internal carotid artery aneurysm. The authors highlight the importance of considering...
