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RaScaL Study

The RaScaL study was a six month, single-centre, controlled, prospective phase I/II study in which subjects with diabetic macular oedema (DME) and associated peripheral nonperfusion on ultrawide-field fluorescein angiography (UWFA) were randomised to: (1) study arm: ranibizumab (0.5 mg) injection...

Part 1: Good news, bad news at the international conference

One of my favourite comic strips from my childhood was Good News, Bad News which ran in Jackpot comic from 1979–1982. In this strip, the story for the main character would be described in a series of alternating ‘Good News’...

Comparison of changes in ECD and CCT between CPS and FLACS

This is an intraindividual randomised clinical trial of 134 eyes from 67 patients, one eye was treated with femtosecond laser-assisted cataract surgery (FLACS) (including pretreatment of main incision, side port, capsulotomy and lens fragmentation) and the fellow eye received conventional...

Surgeons can lead the way in transforming global health

Surgeons must provide leadership in transforming healthcare across the Global South – by integrating surgery into the global health agenda and advocating for simple and cost-effective surgical procedures that support overall health system strengthening.

Rebound phenomenon after IVT triamcinolone acetonide for macular oedema

In this retrospective study, the authors report the rebound phenomenon after intravitreal triamcinolone acetonide (IVTA) injection for macular oedema secondary to diabetic retinopathy (DR) and central (CRVO) or branch retinal vein occlusion (BRVO). The incidence of a rebound phenomenon was...

Association between neurodegeneration and macular perfusion in the progression of diabetic retinopathy

In this prospective three-year longitudinal study, the authors aimed to explore the relation between retinal neurodegenerative changes and vessel closure (VC) in individuals with non-proliferative diabetic retinopathy (NPDR). The participants included 74 individuals with type 2 diabetes, NPDR, and Early...

ILM peeling in proliferative diabetic retinopathy: a meta-analysis

This meta-analysis highlights the efficacy of internal limiting membrane (ILM) peeling on treating posterior segment complications other than macular oedema in patients with proliferative diabetic retinopathy (PDR) treated with vitrectomy. PubMed, EMBASE and Cochrane Library were searched for databases. Eleven...

Comparison of the efficacy of anti-VEGFs agents in nvAMD

This retrospective multicentric study conducted in Israel and Canada, compared the efficacy of bevacizumab, aflibercept 2mg and ranibizumab as first-line treatments for neovascular age-related macular degeneration (nvAMD). Included were treatment-naïve nvAMD eyes receiving ≥12 months of treat-and-extend (T&E) anti-VEGF therapy...

University of Birmingham hosts major global conference on green surgery

The University of Birmingham is bringing together clinicians, policy makers, and industry for a second major conference aimed at reducing the healthcare sector’s contribution to climate change. Registrations are now open for the Research for Greener Surgery Conference 2024, which...

Conference Preview: SightCare LIVE 2026

New dates. New location. Same unmissable experience. SightCare is delighted to announce that SightCare LIVE 2026 – the flagship conference, awards and exhibition – will take place on Sunday 26 and Monday 27 April 2026 at an exciting new venue:...

RCOphth: Portfolio Pathway Training Day

The Royal College of Ophthalmologists: Portfolio Pathway Training Day

Establishing an intra-arterial chemotherapy service for children with retinoblastoma in Nigeria for the first time

This is the first in a series of three articles (see Part 2 here) about strengthening eye health services in Nigeria through collaboration with the LINKS and Networks run at the International Centre for Eye Health, London School of Hygiene...